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Explain why a transplant tissue would be rejected if that tissue had different HLAs compared to the HLAs of the recipient. How can this rejection be decreased?

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When a transplant tissue has different h...

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All of the following are false regarding Herceptin EXCEPT


A) it neutralizes the growth factor EGF.
B) it is a vaccine to prevent the development of cancer.
C) it acts as an immunotoxin to target and kill cancer cells.
D) it is an endotoxin that stimulates TNF by macrophages.
E) it is used to treat some breast cancer patients.

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Which antibodies will be in the serum of a person with blood type B, Rh+?


A) anti- B
B) anti- B, anti- Rh
C) anti- A, anti- Rh
D) anti- A, anti- B, anti- Rh
E) anti- A

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Hemolytic disease of the newborn can result from an


A) Rh- mother with an Rh+ fetus.
B) AB mother with an O fetus.
C) Rh+ mother with an Rh- fetus.
D) Rh- mother and an A fetus.
E) AB mother with a B fetus.

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Treatment with certain drugs to reduce transplant rejection can cause


A) immunologic surveillance.
B) immunotherapy.
C) immunologic enhancement.
D) immunosuppression.
E) autoimmunity.

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Which of the following statements about type I reactions is FALSE?


A) The symptoms are due to histamine.
B) They involve helper T cells.
C) Antibodies bind to mast cells and basophils.
D) The symptoms occur soon after exposure to an antigen.
E) They involve IgE antibodies.

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Which of the following is the least likely vaccine against HIV?


A) subunit
B) glycoprotein
C) protein core
D) attenuated virus
E) All of these vaccines are equally likely.

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The process of desensitization to prevent allergies involves the injection of increasing amounts of


A) RhoGAM.
B) antihistamine.
C) IgE.
D) antigen.
E) IgG.

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Figure 19.1 Figure 19.1    -In immune complex reaction shown in Figure 19.1, what is the structure labeled  a ? A)  complement B)  antigen C)  mast cell D)  antibody E)  neutrophil -In immune complex reaction shown in Figure 19.1, what is the structure labeled "a"?


A) complement
B) antigen
C) mast cell
D) antibody
E) neutrophil

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Which of the following describes a cytotoxic autoimmune reaction?


A) Antibodies are not made.
B) Antibodies react to cell- surface antigens.
C) Mediate by T cells.
D) Cells are killed.
E) Immune complexes form.

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Allergic contact dermatitis is due to


A) activated macrophages.
B) sensitized T cells.
C) IgM antibodies.
D) IgG antibodies.
E) IgE antibodies.

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Immunodeficiencies are a result of all of the following EXCEPT


A) DiGeorge syndrome.
B) autoimmune diseases.
C) cyclosporine.
D) Hodgkin's disease.
E) HIV infection.

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HIV attack of CD4+ T cells causes suppression of both cell- mediated and humoral immune responses.

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All hypersensitivities involve antibody- antigen reactions.

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Figure 19.1 Figure 19.1    -In immune complex reaction shown in Figure 19.1, what is the end result of the reaction? A)  IgG is directed against cell membrane antigens. B)  Endothelial cells are damaged. C)  Antibodies destroy neutrophils. D)  Complement is activated. E)  Neutrophils are attracted and release enzymes. -In immune complex reaction shown in Figure 19.1, what is the end result of the reaction?


A) IgG is directed against cell membrane antigens.
B) Endothelial cells are damaged.
C) Antibodies destroy neutrophils.
D) Complement is activated.
E) Neutrophils are attracted and release enzymes.

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A healthy immune system destroys cancer cells with


A) CTLs.
B) activated macrophages.
C) CD+ T cells.
D) CTLs and activated macrophages.
E) tumor- specific antigens.

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Individuals who do not express CCR5 are highly resistant to infection by HIV.

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Which of the following statements about type IV reactions is FALSE?


A) Reactions are not apparent for a day or more.
B) Reactions are primarily due to T cell proliferation.
C) Cytokines initiate tissue damage.
D) Allergic contact dermatitis is an example.
E) Hemolytic disease of the newborn is an example.

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All stem cells are derived from embryonic stem cells.

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Attachment of HIV to the target cell depends on


A) gp120 combining with the chemokine receptor CCR5.
B) gp120 combining with the CD4+ receptor.
C) CXCR4 binding to the CD4+ receptor.
D) gp120 binding to the CD4+ plasma membrane.
E) gp41 binding to the CD4+ receptor.

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