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Using phages to treat a bacterial infection is an interesting idea because


A) a single type of phage can destroy a wide range of strains of the same pathogen.
B) of the increasing problem of antibiotic resistance in pathogens.
C) lysed bacteria pose no threat to a person's health.
D) a single phage can be genetically engineered to infect many different species of bacteria.
E) of the increasing problem of antibiotic resistance in people.

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Retroviruses are unique in that they


A) replicate in nervous system cells.
B) use RNA as a template to make DNA.
C) do not have a capsid.
D) use DNA as a template to make RNA.
E) use RNA as a template to make more RNA.

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The protein projections on the surface of a virus that are involved in attachment to the host cell are called


A) suckers.
B) pili.
C) cilia.
D) spikes.
E) hooks.

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The activation of the SOS system in a bacterium infected with a prophage results in


A) destruction of certain bacterial genes AND destruction of the viral repressor through host protease activity.
B) destruction of the viral repressor through host protease activity AND complete lysis of the bacterial culture.
C) destruction of the viral repressor through host protease activity AND mutation of the DNA
D) complete lysis of the bacterial culture, destruction of the viral genes, AND mutation of the DNA.
E) destruction of certain bacterial genes AND complete lysis of the bacterial culture.

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Why is it not surprising that AIDS patients frequently suffer a viral-induced tumor?


A) HIV genomes integrate into the host cell chromosome. This integration might result in loss of control of the cell cycle (also known as cancer) .
B) The immune system's CD4+ T cells are directly responsible for elimination of tumor cells. HIV attacks them and eliminates them, making a person more susceptible to cancer.
C) The therapies for HIV are highly mutagenic, which may lead to cancerous states in people taking the drug regimen.
D) Products of an active HIV infection are highly mutagenic; as a person's illness progresses, these compounds build up and induce a cancerous state.
E) The DNA polymerases of people with AIDS lose any proofreading ability, so any mistakes that happen during DNA replication automatically lead to development of cancer.

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Why is it virtually impossible to eradicate a disease caused by a zoonotic virus?


A) You would have to drive the vector organism extinct to do so.
B) Many vector organisms have multiple stages of their life cycle that can carry a zoonotic virus, which complicates controlling the vector-borne transmission.
C) Many viruses transmitted in this manner may utilize more than one vector organism.
D) Many zoonotic viruses may be able to reside in more than one host organism, complicating control measures.
E) All of the answer choices are correct.

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Attachment of animal viruses to the host cell may be by means of


A) a tail.
B) the envelope.
C) spikes.
D) a capsid.
E) a membrane.

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The genome of retroviruses is made of


A) ssDNA.
B) dsDNA.
C) ssRNA.
D) dsRNA.
E) protein and RNA.

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What part of the attached bacteriophage enters through the host cell wall?


A) The entire virus.
B) Only the enzymes necessary for replication.
C) The nucleic acid.
D) The nucleic acid and capsid.
E) The capsid only.

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A lysogenic cell contains viral DNA (a prophage) integrated into the host chromosome.

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Assembly of the T4 phage


A) is completely self-assembly
B) is completely dependent on scaffolds.
C) may involve some self-assembly AND may involve the use of scaffolds.
D) may involve some self-assembly AND is completely dependent on scaffolds.
E) is completely self-assembly AND is never dependent on scaffolds.

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The site at which a virus has infected and subsequently lysed the infected cell, releasing its progeny to infect and lyse surrounding cells, thereby forming a "clear zone," is


A) a burst area.
B) a lyse area.
C) a plaque.
D) a dead zone.
E) a zone of inhibition.

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Animal viruses are divided into a number of families whose names end in


A) -virus.
B) -viridae.
C) -viscous.
D) -eieio.
E) -virum.

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There are ________ major families of RNA containing viruses that infect vertebrates.


A) 2
B) 5
C) 7
D) 13
E) 6

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Capsids are made of a number of capsomeres that are covalently bonded to one another.

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What are two ways that phage can replicate without directly lysing their host cell?


A) Conjugation and lysogeny
B) Lysogeny and transduction
C) Extrusion and transformation
D) Extrusion and lysogeny
E) Extrusion and lysis

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Normal tissue taken from animals and prepared immediately as a medium for viral growth is termed a(n)


A) advantageous group.
B) monolayer culture.
C) primary culture.
D) plaque.
E) virus culture.

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A virion is a(n)


A) pathogenic virus.
B) subviral particle.
C) complete, extracellular virus particle.
D) enveloped virus particle.
E) non-enveloped virus particle.

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The terms helical, icosahedral, and complex refer to


A) viral life cycles.
B) forms of nucleic acid.
C) types of viral envelopes.
D) shapes of viruses.
E) types of bacteriophages.

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Prions affect the


A) respiratory system.
B) gastrointestinal tract.
C) nervous system.
D) lymphatic system.
E) urogenital system.

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