Question 1

Each of the following organelles is part of the endomembrane system except

Accepted Answer

A)  the peroxisome.
B)  the Golgi complex.
C)  the smooth endoplasmic reticulum.
D)  the endosome.
E)  the rough endoplasmic reticulum.

Question 2

A COPII-coated vesicle has all of the following except

Accepted Answer

A)  Sec 13/31.
B)  Sec 23/34.
C)  v-SNARE.
D)  Sar1.
E)  AP-2.

Question 3

Design an experiment that will allow you to follow a protein from its synthesis to constitutive secretion from the cell.Where would you expect to find the protein at different times during the process? How would the pathway differ if the protein obtained a mannose-6-phosphate modification during transit?

Accepted Answer

The newly synthesized protein must be la...

Question 4

Exocytosis is stimulated by regional increases in cytoplasmic ________ concentration.

Accepted Answer

The answer of Exocytosis is stimulated by regional increases in...

Question 5

The plant cell organelle most analogous to animal cell lysosomes is the

Accepted Answer

A)  vacuole.
B)  glyoxysome.
C)  microsome.
D)  endosome.
E)  leaf peroxisome.

Question 6

Each of the following is a lysosomal storage disease caused by a deficiency in lysosomal enzymes except

Accepted Answer

A)  familial hypercholesterolemia.
B)  Hurler syndrome.
C)  Hunter syndrome.
D)  type II glycogenosis.
E)  Tay-Sachs disease.

Question 7

Which of the following statements is false regarding phagocytosis?

Accepted Answer

A)  It can ingest large particles.
B)  It involves the projection of pseudopods.
C)  It is used by amoebae to ingest food.
D)  It is mediated by clathrin at the plasma membrane.
E)  It is used by macrophages and neutrophils to ingest bacteria.

Question 8

V- and t-________ mediate final docking between vesicle and target membranes.

Accepted Answer

The answer of V- and t-________ mediate final docking between...

Question 9

Peroxisomes and the smooth endoplasmic reticulum are both associated with detoxification of harmful substances.How do these two organelles differ with regard to this process?

Accepted Answer

sER: Enzyme-catalyzed hydroxylation make...

Question 10

A protein that is normally localized in the cytoplasm has been engineered so that it will be secreted from the cell instead.Which of the following represents the most likely pathway for the protein after it has been completely synthesized?

Accepted Answer

A)  rER → Golgi → secretory vesicle → environment
B)  rER → Golgi → sER → cytoplasm → environment
C)  cytoplasm → rER → Golgi → secretory vesicle → environment
D)  sER → Golgi → secretory vesicle → environment
E)  rER → secretory vesicle → Golgi → environment

Question 11

Each of the following is part of the core oligosaccharide side chain in the ER except

Accepted Answer

A)  N-acetyl glucosamine.
B)  erythrose.
C)  mannose.
D)  glucose.
E)  All are part of the core oligosaccharide.

Question 12

Using genetic engineering techniques,which of the following would you do to a protein that normally is constitutively secreted to make it accumulate in the ER?

Accepted Answer

A)  fuse it to GFP
B)  add an amino acid that would get a mannose-6-phosphate group added to its carbohydrate
C)  add a KDEL sequence near its C-terminus
D)  mutate one of the asparagines that is normally glycosylated to an alanine,which is not glycosylated
E)  None of these would cause the protein to accumulate in the ER.

Question 13

In animal cells,oxidation of very long fatty acids occurs in

Accepted Answer

A)  mitochondria.
B)  peroxisomes.
C)  lysosomes.
D)  the smooth endoplasmic reticulum.
E)  residual bodies.

Question 14

Pancreatic acinar cells produce and store hydrolytic enzymes in zymogen granules until hormones signal the cell to release the enzymes in a process known as

Accepted Answer

A)  transport secretion.
B)  regulated secretion.
C)  constitutive secretion.
D)  intracellular secretion.
E)  consistent secretion.

Question 15

________ is the organelle associated with the functions of steroid biosynthesis,carbohydrate metabolism,and drug detoxification.

Accepted Answer

Smooth end...

Question 16

In a lysosomal storage disease,newly synthesized lysosome hydrolases are secreted from the cells rather than being delivered to the lysosomes.What is one possible mechanism for this result?

Accepted Answer

A)  The cis-Golgi network lacks a proton gradient.
B)  The ER is unable to produce lysosomal vesicles.
C)  Lysosomal enzymes are not phosphorylated in the rER.
D)  Mannose is not phosphorylated in the cis-Golgi network.
E)  All the hydrolase genes are mutated,resulting in synthesis by ribosomes free in the cytoplasm rather than on the endoplasmic reticulum membrane.

Question 17

Each of the following is an endoplasmic reticulum function except

Accepted Answer

A)  addition of carbohydrate to proteins to make glycoproteins.
B)  peptide folding.
C)  the assembly of multimeric proteins.
D)  the export of protein that cannot be folded into the cytoplasm for destruction.
E)  All are endoplasmic reticulum functions.

Question 18

Comparing cells synthesizing secretory proteins and cells secreting steroid hormones,the cells synthesizing the steroid hormones have

Accepted Answer

A)  more rough ER.
B)  more smooth ER.
C)  equal amounts of smooth and rough ER.
D)  equal amounts of smooth and rough ER,but more lysosomes.
E)  equal amounts of smooth and rough ER,but fewer lysosomes.

Question 19

The ________ is the organelle that fuses with endosomes and supplies hydrolytic enzymes necessary for the digestion of the materials.

Accepted Answer

The answer of The ________ is the organelle that fuses...

Question 20

On which of the following intracellular locations does clathrin organize a coat and form vesicles?

Accepted Answer

A)  lysosomes
B)  trans-Golgi complex
C)  endoplasmic network
D)  inner membrane of mitochondria
E)  regulated secretory vesicles

Exam 12: The Endomembrane System

The plant cell organelle most analogous to animal cell lysosomes is the

Correct Answer
verified

Each of the following is an endoplasmic reticulum function except

Correct Answer
verified

On which of the following intracellular locations does clathrin organize a coat and form vesicles?

Correct Answer
verified

The ________ is the organelle that fuses with endosomes and supplies hydrolytic enzymes necessary for the digestion of the materials.

Correct Answer
verified

Each of the following is a lysosomal storage disease caused by a deficiency in lysosomal enzymes except

Correct Answer
verified

A protein that is normally localized in the cytoplasm has been engineered so that it will be secreted from the cell instead.Which of the following represents the most likely pathway for the protein after it has been completely synthesized?

Correct Answer
verified

Each of the following organelles is part of the endomembrane system except

Correct Answer
verified

Each of the following is part of the core oligosaccharide side chain in the ER except

Correct Answer
verified

Comparing cells synthesizing secretory proteins and cells secreting steroid hormones,the cells synthesizing the steroid hormones have

Correct Answer
verified

Exocytosis is stimulated by regional increases in cytoplasmic ________ concentration.

Correct Answer
verified

A COPII-coated vesicle has all of the following except

Correct Answer
verified

Correct Answer
verified
The newly synthesized protein must be la...
View Answer

Using genetic engineering techniques,which of the following would you do to a protein that normally is constitutively secreted to make it accumulate in the ER?

Correct Answer
verified

V- and t-________ mediate final docking between vesicle and target membranes.

Correct Answer
verified

Which of the following statements is false regarding phagocytosis?

Correct Answer
verified

In animal cells,oxidation of very long fatty acids occurs in

Correct Answer
verified

Pancreatic acinar cells produce and store hydrolytic enzymes in zymogen granules until hormones signal the cell to release the enzymes in a process known as

Correct Answer
verified

Peroxisomes and the smooth endoplasmic reticulum are both associated with detoxification of harmful substances.How do these two organelles differ with regard to this process?

Correct Answer
verified
sER: Enzyme-catalyzed hydroxylation make...
View Answer

________ is the organelle associated with the functions of steroid biosynthesis,carbohydrate metabolism,and drug detoxification.

Correct Answer
verified
Smooth end...
View Answer

In a lysosomal storage disease,newly synthesized lysosome hydrolases are secreted from the cells rather than being delivered to the lysosomes.What is one possible mechanism for this result?

Correct Answer
verified

Exam 12: The Endomembrane System

The plant cell organelle most analogous to animal cell lysosomes is the

Correct AnswerverifiedShow Answer

Each of the following is an endoplasmic reticulum function except

Correct AnswerverifiedShow Answer

On which of the following intracellular locations does clathrin organize a coat and form vesicles?

Correct AnswerverifiedShow Answer

The ________ is the organelle that fuses with endosomes and supplies hydrolytic enzymes necessary for the digestion of the materials.

Correct AnswerverifiedShow Answer

Each of the following is a lysosomal storage disease caused by a deficiency in lysosomal enzymes except

Correct AnswerverifiedShow Answer

A protein that is normally localized in the cytoplasm has been engineered so that it will be secreted from the cell instead.Which of the following represents the most likely pathway for the protein after it has been completely synthesized?

Correct AnswerverifiedShow Answer

Each of the following organelles is part of the endomembrane system except

Correct AnswerverifiedShow Answer

Each of the following is part of the core oligosaccharide side chain in the ER except

Correct AnswerverifiedShow Answer

Comparing cells synthesizing secretory proteins and cells secreting steroid hormones,the cells synthesizing the steroid hormones have

Correct AnswerverifiedShow Answer

Exocytosis is stimulated by regional increases in cytoplasmic ________ concentration.

Correct AnswerverifiedShow Answer

A COPII-coated vesicle has all of the following except

Correct AnswerverifiedShow Answer

Correct AnswerverifiedThe newly synthesized protein must be la...View AnswerShow Answer

Using genetic engineering techniques,which of the following would you do to a protein that normally is constitutively secreted to make it accumulate in the ER?

Correct AnswerverifiedShow Answer

V- and t-________ mediate final docking between vesicle and target membranes.

Correct AnswerverifiedShow Answer

Which of the following statements is false regarding phagocytosis?

Correct AnswerverifiedShow Answer

In animal cells,oxidation of very long fatty acids occurs in

Correct AnswerverifiedShow Answer

Pancreatic acinar cells produce and store hydrolytic enzymes in zymogen granules until hormones signal the cell to release the enzymes in a process known as

Correct AnswerverifiedShow Answer

Peroxisomes and the smooth endoplasmic reticulum are both associated with detoxification of harmful substances.How do these two organelles differ with regard to this process?

Correct AnswerverifiedsER: Enzyme-catalyzed hydroxylation make...View AnswerShow Answer

________ is the organelle associated with the functions of steroid biosynthesis,carbohydrate metabolism,and drug detoxification.

Correct AnswerverifiedSmooth end...View AnswerShow Answer

In a lysosomal storage disease,newly synthesized lysosome hydrolases are secreted from the cells rather than being delivered to the lysosomes.What is one possible mechanism for this result?

Correct AnswerverifiedShow Answer

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verified
The newly synthesized protein must be la...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
sER: Enzyme-catalyzed hydroxylation make...
View Answer

Correct Answer
verified
Smooth end...
View Answer

Correct Answer
verified