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In the female reproductive cycle, is/are normally produced every 28 days.


A) two ova
B) millions of sperm
C) several ova
D) a single sperm
E) a single ovum

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Which of the following is the correct order of sperm development?


A) spermatogonia, primary spermatocyte, secondary spermatocyte, spermatid, spermatozoa
B) spermatozoa, spermatogonia, primary spermatocyte, secondary spermatocyte, spermatid
C) spermatid, secondary spermatocyte, primary spermatocyte, spermatogonia, spermatozoa
D) spermatid, primary spermatocyte, secondary spermatocyte, spermatogonia , spermatozoa
E) spermatogonia primary spermatocyte, secondary spermatocyte, spermatozoa, spermatid

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Most of the uterine wall thickness is composed of smooth muscle known as the


A) myometrium.
B) perimetrium.
C) endometrium.
D) parametrium.
E) epimetrium.

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The migration of sperm into the uterus, on their way to contact the ovum, is facilitated by the secretion of into the .


A) progesterone : uterine tube
B) an acidic solution : cervical canal
C) estrogen : uterine tube
D) a thin mucus : cervical canal
E) an alkaline solution : uterine tube

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D

What are gonadotrophs?


A) growth factors for sexual differentiation
B) hormones of the gonads
C) cells of the gonads that secrete sex hormones
D) cells of the hypothalamus that secrete GnRH (gonadotropin- releasing hormone)
E) cells of the anterior pituitary that secrete the gonadotropic hormones FSH and LH

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Which of the following represents the chromosome number in a zygote?


A) diploid
B) haploid
C) sex chromosomes
D) alleles
E) autosomes

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If a mother develops gestational diabetes, then both the mother and fetus can suffer from hyperglycemia.

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Fertilization of the ovum usually occurs within the uterus.

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What is the function of the accessory reproductive organs?


A) the secretion of sex hormones only
B) secondary sex characteristics only
C) secretion of fluids into the reproductive tract only
D) transport of gametes only
E) both secretion of fluids into the reproductive tract and transport of gametes

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Sex differentiation depends on the presence or absence of the srY gene, whereas sex determination depends on the presence or absence of testes.

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Which of the following is permissive to the actions of progesterone by inducing expression of progesterone receptors in the endometrium?


A) progesterone
B) inhibin
C) LH
D) FSH
E) estrogens

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Which of the following stimulates prolactin secretion?


A) progesterone
B) LH
C) estrogens
D) FSH
E) inhibin

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How do males continue to produce sperm through their adult lives?


A) Spermatozoa can undergo cell division daily.
B) Sperm cells never die.
C) Testosterone levels remain elevated throughout adulthood.
D) Secondary spermatocytes produce an endless supply of primary spermatocytes.
E) When a spermatogonium undergoes mitosis, only one undergoes further differentiation and meiosis to become a mature sperm; the other stays a spermatogonium.

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The elevated plasma concentration of estrogen early in the luteal phase has little effect on the secretion of luteinizing hormone (LH) because


A) gonadotropin- releasing hormone (GnRH) is reduced.
B) progesterone strongly inhibits LH release.
C) the corpus luteum degenerates.
D) inhibin strongly inhibits LH release.
E) secretin release is inhibited.

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What cells secrete Müllerian inhibiting substance in fetal life?


A) granulosa cell
B) follicle cell
C) Leydig cell
D) Sertoli cell
E) theca cell

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Having one set of 23 chromosomes is called what?


A) diploid
B) haploid
C) sex chromosomes
D) alleles
E) autosomes

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Implantation of the blastocyst into the endometrium results from


A) trophoblast secretion of endocrine hormones that initiates the decidual response.
B) trophoblast secretion of enzymes and paracrines that initiates the decidual response.
C) trophoblast secretion of paracrines that initiates cell cleavage.
D) blastocoele secretion of paracrines that initiates cell cleavage.
E) blastocoele secretion of paracrines that initiates the decidual response.

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Enzymes that facilitate entry of sperm into the ova are contained within the of the spermatozoa.


A) tail
B) midpiece
C) flagella
D) mitochondria
E) acrosome

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Sperm are unable to fertilize the egg upon entry into the vagina and must undergo , allowing them to , which facilitates fertilization.


A) capacitation : activate the acrosome
B) capacitation : more readily adhere to the ovum
C) resistation : move faster
D) implantation : move faster
E) resistation : activate the acrosome

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B

The menstrual cycle is repeated every 28 days and involves changes within the ovaries and the uterus. Describe the changes that occur during the ovarian cycle.

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The ovarian cycle is divided into two phases: the follicular phase and the luteal phase. In the beginning of the follicular phase, about 10- 25 follicles develop. Within seven days, one of those follicles (the dominant follicle)will develop to full maturity. The remaining follicles will undergo atresia and be lost. As the follicles begin to develop, the oocyte grows in size. At the same time, the granulosa cells increase in size and number. This growth is stimulated by follicle- stimulating hormone (FSH)and the estrogens secreted by the follicles. There is also a thick layer of non- cellular material forming around the oocyte called the zona pellucida. At the outer layer of the follicle, theca cells begin to develop. A fluid- filled cavity (antrum)begins to form within the granulosa cell layer. This is the point at which many of the follicles stop their development. Follicles that have not developed adequately to maintain estrogen secretion in the face of decreasing FSH undergo atresia. As follicles develop further, the antrum continues to grow, displacing some of the cellular tissue around the oocyte, leading to a protrusion from the follicular wall (corona radiata). Eventually, the first meiotic division occurs and the secondary oocyte detaches from the follicle wall and floats freely in the antral fluid. The antrum continues to grow until it forms the Graafian follicle, just prior to ovulation. The luteinizing hormone (LH)surge that induces ovulation begins the luteal phase, during which the follicle bursts and the oocyte is released. The granulosa and theca cells of the ruptured follicle are transformed into the corpus luteum that secretes the estrogen and progesterone that prepare the uterus for implantation. In the absence of fertilization, the corpus luteum begins to degrade after ten days, reducing plasma estrogens and progesterone concentration, thereby initiating menstruation.

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