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All of the following are considered examples of type I hypersensitivity EXCEPT


A) dust allergies.
B) pollen allergies.
C) transplant rejections.
D) asthma.
E) penicillin allergic reactions.

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Allergic contact dermatitis is due to


A) activated macrophages.
B) sensitized T cells.
C) IgE antibodies.
D) IgM antibodies.
E) IgG antibodies.

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Worldwide, the primary method of transmission of HIV is


A) blood transfusions.
B) nosocomial.
C) heterosexual intercourse.
D) homosexual intercourse.
E) intravenous drug use.

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All stem cells are derived from embryonic stem cells.

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The chemical mediators of anaphylaxis are


A) antigen-antibody complexes.
B) the proteins of the complement system.
C) antigens.
D) found in basophils and mast cells.
E) antibodies.

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HIV attack of CD4+ T cells causes suppression of both cell-mediated and humoral immune responses.

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Table 19.1  Donor  Recipient  1. AB,RhAB,Rh+ 2. A,Rh+A+,Rh 3. A,Rh+O,Rh+ 4. B, RhB,Rh+ 5. B, Rh+A,Rh+\begin{array} { | l | l | } \hline \text { Donor } & \text { Recipient } \\\hline \text { 1. } \mathrm { AB } , \mathrm { Rh } ^ { - } & \mathrm { AB } , \mathrm { Rh } ^ { + } \\\hline \text { 2. } \mathrm { A } , \mathrm { Rh } ^ { + } & \mathrm { A } ^ { + } , \mathrm { Rh } ^ { - } \\\hline \text { 3. } \mathrm { A } , \mathrm { Rh } ^ { + } & \mathrm { O } , \mathrm { Rh } ^ { + } \\\hline \text { 4. B, } \mathrm { Rh } ^ { - } & \mathrm { B } , \mathrm { Rh } ^ { + } \\\hline \text { 5. B, } \mathrm { Rh } ^ { + } & \mathrm { A } , \mathrm { Rh } ^ { + } \\\hline\end{array} Which blood transfusions in Table 19.1 are incompatible?


A) 1, 2, and 3
B) 2 and 5
C) 3 and 4
D) 1 and 2
E) 2, 3, and 5

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Which antibodies will be in the serum of a person with blood type B, Rh+?


A) anti-A, anti-B, anti-Rh
B) anti-A
C) anti-A, anti-Rh
D) anti-B
E) anti-B, anti-Rh

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All of the following pertain to serological tests EXCEPT


A) they are used to test for specific HLAs on lymphocytes.
B) they can be used to diagnose various diseases.
C) they can detect antibodies but not antigens.
D) they are used to detect compatible tissues for transplantation.
E) reactions can be detected by uptake of trypan blue by damaged cells.

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Vaccines against HIV have proven to be very effective in halting the spread of disease.

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All of the following lead to drug-induced thrombocytopenic purpura. Which occurs first?


A) Antibodies and complement react with platelets.
B) Platelets are destroyed.
C) Purpura occurs on the skin.
D) Antibodies against haptens are formed.
E) Drug binds to platelets.

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Cancer is similar to an infectious disease in that it is due to a failure of the bodyʹs defenses.

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Hemolytic disease of the newborn can result from an


A) Rh- mother and an A fetus.
B) Rh+ mother with an Rh- fetus.
C) Rh- mother with an Rh+ fetus.
D) AB mother with an O fetus.
E) AB mother with a B fetus.

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A positive tuberculin skin test is an example of


A) delayed cell-mediated immunity.
B) autoimmunity.
C) innate immunity.
D) psoriasis.
E) acute contact dermatitis.

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Individuals who do not express CCR5 are highly resistant to infection by HIV.

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All of the following are true of hypersensitivity EXCEPT


A) it is due to an altered immune response.
B) it requires previous exposure to an antigen.
C) it is synonymous with ʺallergy.ʺ
D) it occurs when an individual is exposed to an allergen for the first time.
E) it occurs in the presence of an antigen.

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When testing donated blood for compatibility you would find a person with O type blood


A) will lack plasma antibodies to A and B type antigens.
B) has O type antigens on their red blood cells.
C) will have anti-O antibodies in their plasma.
D) lacks HLA and MHC antigens.
E) will lack A and B red blood cell antigens.

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All of the following are reasons why an HIV vaccine has not been developed EXCEPT


A) there is no known animal model of natural immunity for HIV infection.
B) vaccines are not effective against viral infections.
C) small, inexpensive animals which could be used for HIV vaccine research are not available.
D) HIV has a high mutation rate so one vaccination would not be effective to treat the world-wide pandemic.
E) use of a weakened virus would potentially transmit the infection.

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A hypersensitivity reaction refers to immune responses to antigens beyond what would be normal.

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Which of the following may result from systemic anaphylaxis?


A) immunodeficiency
B) shock
C) asthma
D) hay fever
E) hives

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