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A 10-year-old child is diagnosed with major depression. The appropriate first-line antidepressant for children is:


A) Fluoxetine
B) Fluvoxamine
C) Sertraline
D) Escitalopram

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An overweight patient recently started taking topiramate for seizures and at her follow-up visit you note she has lost 3 kg. The appropriate action would be:


A) Tell her to increase her caloric intake to counter the effects of the topiramate.
B) Consult with a neurologist, as this is not a common adverse effect of topiramate.
C) Decrease her dose of topiramate.
D) Reassure her that this is a normal side effect of topiramate and continue to monitor her weight.

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An adult female is taking valproate (Depakote) for seizures and would like to get pregnant. What advice would you give her?


A) Valproate is safe during all trimesters of pregnancy.
B) She can get pregnant while taking valproate, but she should take adequate folic acid.
C) Valproate is not safe at any time during pregnancy.
D) Valproate is a known teratogen, but may be taken after the first trimester if necessary.

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In choosing a benzodiazepam to treat anxiety the prescriber needs to be aware of the possibility of dependence. The benzodiazepam with the greatest likelihood of causing rapidly developing dependence is:


A) Chlordiazepoxide (Librium)
B) Clonazepam (Klonopin)
C) Alprazolam (Xanax)
D) Oxazepam (Serax)

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A patient is taking lamotrigine (Lamictal) for their seizures and requests a prescription for combined oral contraceptives (COCs) , which interact with lamotrigine and may cause:


A) Contraceptive failure
B) Excessive weight gain
C) Reduced lamotrigine levels, requiring doubling the dose of lamotrigine
D) Induction of estrogen metabolism, requiring higher estrogen content OCs to be prescribed

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A three-year-old child has a history of status epilepticus. Along with her routine antiseizure medication, she should also have a home prescription for _________ to be used for an episode of status epilepticus.


A) IV phenobarbital
B) Rectal diazepam (Diastat)
C) IV phenytoin (Dilantin)
D) Oral carbamazepine (Tegretol)

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A patient with anxiety and depression may respond to:


A) Duloxetine (Cymbalta)
B) Fluoxetine (Prozac)
C) Oxazepam (Serax)
D) Buspirone (Buspar) and an SSRI combined

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A 42-year-old female requests a prescription for an anorexiant to treat her obesity. A trial of phentermine is prescribed. Prescribing precautions include:


A) Understanding that obesity is a contraindication to prescribing phentermine
B) Anorexiants may cause tolerance and should only be prescribed for six months
C) Patients should be monitored for postural hypotension
D) Renal function should be monitored closely while on anorexiants

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A patient is started on paroxetine (Paxil) , an SSRI, for depression. Education regarding antidepressants includes:


A) SSRIs may take two to six weeks before she will have maximum drug effects.
B) Red-green color blindness may occur and should be reported.
C) If she experiences dry mouth or a heart rate greater than 80, she should stop taking the drug immediately.
D) She should eat lots of food high in fiber to prevent constipation.

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Monitoring of a patient on gabapentin to treat seizures includes:


A) Routine testing of therapeutic drug levels every three to four months
B) Assessing for dermatologic reactions, including Steven's Johnson
C) Routine testing of serum electrolytes, especially in hot weather
D) Recording seizure frequency, duration, and severity

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Tricyclic antidepressants should be prescribed cautiously in patients with:


A) Eczema
B) Asthma
C) Diabetes
D) Heart disease

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Scott's seizures are well controlled on topiramate and he wants to start playing baseball. Education for Scott regarding his topiramate includes:


A) He should not play sports due to the risk of increased seizures
B) He should monitor his temperature and ability to sweat in the heat while playing
C) Reminding him that he may need higher doses of topiramate when exercising
D) Encouraging him to use sunscreen due to photosensitivity from topiramate

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A six-year-old has recently started taking ethosuximide (Zarontin) for seizures. The patient should be monitored for:


A) Increased seizure activity, as this drug may autoinduce seizures
B) Altered renal function, including renal failure
C) Blood dyscrasias, which is uncommon but possible
D) Central nervous system (CNS) excitement, leading to insomnia

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A child is prescribed phenytoin for seizures. Monitoring includes assessing:


A) For phenytoin hypersensitivity syndrome three to eight weeks after starting treatment
B) For pedal edema throughout therapy
C) Heart rate at each visit, as therapy may have to be altered if heart rate is less than 60 beats per minute (bpm)
D) For vision changes, such as red-green blindness, at least annually

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When prescribing an opioid analgesic such as acetaminophen and codeine (Tylenol #3) , instructions to the patient should include:


A) The medication may cause sedation and they should not drive.
B) Constipation is a common side effect and they should increase fluids and fiber.
C) Patients should not take any other acetaminophen-containing medications at the same time.
D) All of the above

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Levetiracetam has known drug interactions with:


A) Combined oral contraceptives
B) Carbamazepine
C) Warfarin
D) Few, if any, drugs

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An 8-year-old male has attention deficit disorder (ADD) and is prescribed methylphenidate (Ritalin) . He and his parents should be educated about the side effects of methylphenidate, which are:


A) Slurred speech and insomnia
B) Bradycardia and confusion
C) Dizziness and orthostatic hypotension
D) Insomnia and decreased appetite

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When prescribing temazepam (Restoril) for insomnia, patient education includes:


A) Take temazepam nightly approximately 15 minutes before bedtime.
B) Temazepam should not be used more than three times a week for less than three months.
C) Drinking one ounce of alcohol will cause additive effects and the patient will sleep better.
D) Exercise for at least 30 minutes within two hours of bedtime to enhance the effects of temazepam.

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