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A composite transposon will contain only genes that are necessary for transposition.

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Insertion sequences can be identified by which of the following?


A) Presence of an integrase enzyme
B) High level of mutation
C) Presence of inverted repeats at the end of the sequence
D) Presence of a reverse transcriptase enzyme
E) All of the answers are correct

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What is the selfish DNA theory?


A) A theory that explains how DNA point mutations are repaired within the genome.
B) A theory that explains how transposable elements are repaired within the genome.
C) A theory that attempts to explain the proliferation of transposable elements in a genome by comparing it to the action of a parasite.
D) None of the above

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Which of the following processes accounts for the tremendous variation in antibody structure?


A) RNA editing
B) Site-specific recombination
C) Integrase activity
D) Physiological adaptation
E) Hot spots of mutation in the immunoglobin genes

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To date, there are not any indications that transposable elements offer a selective advantage to a species.

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An attachment site for bacteriophage l have which of the following characteristic(s) ?


A) Specific proteins in the cell membrane
B) A unique set of phospholipids that identify the organelle of interest
C) A lack of a cell wall
D) A specific DNA sequence that is recognized by the integrase enzyme
E) None of the answers are correct

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Which of the following enzymes is required for a transposon to move?


A) Integrase
B) Jumpase
C) Splicase
D) Transposase
E) None of the answers are correct

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In eukaryotic organisms, a single-stranded break in the DNA is required before recombination can begin during meiosis.

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The integrase enzyme is responsible for inserting bacteriophage l into the host genome.

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The formation of a D-loop is associated with which of the following models of recombination?


A) Double-stranded break model
B) Holliday model
C) Single-stranded break model
D) All of the answers are correct

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All light chain polypeptides in an immunoglobin contain which of the following?


A) A C region
B) A V region
C) A J region
D) All of the answers are correct

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Transposons that utilize an RNA intermediate for transposition are called .


A) Retro elements
B) Retroposons
C) Retrotransposons
D) All of the answers are correct

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Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?


A) Ds
B) C
C) Sh
D) Wx
E) All of the answers are correct

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Transposase is involved with removing the transposable element from its current location.

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The individual who first proposed the existence of transposable elements was .


A) Sturtevant
B) Morgan
C) McClintock
D) Franklin
E) Watson

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RAG1 and RAG2 proteins are associated with which of the following?


A) Recombination during prophase I of meiosis
B) Nucleotide excision repair
C) Transposition
D) Integration of a bacteriophage into the host genome
E) Site-specific recombination in antibody genes

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A bacteriophage that has integrated into the bacterial chromosome is called a prophage.

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As a researcher, you have identified a potential transposable element that contains both a transposase and resolvase enzyme. Which of the following types of transposons would you assign it to based on this information?


A) Composite transposon
B) Non-viral retro element
C) Viral-like retro element
D) Replicative transposon
E) Insertion sequence

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Which of the following is incorrect regarding immunoglobins?


A) They are produced by B cells
B) They recognize a specific epitope
C) The human genome contains a unique gene for each immunoglobin produced
D) They are all proteins

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