Question 1

Antimicrobials effective against a wide variety of microbial types are termed ______.

Accepted Answer

A)   antibiotics
B)   narrow-spectrum drugs
C)   semisynthetic drugs
D)   synthetic drugs
E)   broad-spectrum drugs

Question 2

Which of the following is not a therapeutic beneﬁt of interferon?

Accepted Answer

A)   Reduces healing time
B)   Increases white blood cell count
C)   Prevents or reduces some cold symptoms
D)   Slows progress of some cancers
E)   Treats hepatitis C

Question 3

A patient has a staphylococcal infection of the blood; a septicemia - very serious and possibly deadly. As the doctor, you would like to prescribe a relatively non-toxic and inexpensive drug out of the cephalosporin family. However, if the patient harbors a strain of Staphylococcus that is resistant
To a variety of antibiotics, you would prefer to use vancomycin-- which is highly effective against staphylococcus. Which of the following explains why the cephalosporin drug is preferred for use over the vancomycin?

Accepted Answer

A)   You would rather give an inexpensive drug to save the family money.
B)   You really do not know that much about vancomycin, so you would rather go with a drug that you can ?nd out more about.
C)   Vancomycin is very toxic, and the Staphylococcus strain could become resistant leaving no back-up drugs with which to treat the infection.
D)   Vancomycin is one of the most selectively toxic drugs there is, so you would prefer one that has a more broad-spectrum effect. C

Question 4

A drug exhibiting which therapeutic index value would be the safest, most effective to use on a patient?

Accepted Answer

A)   20
B)   10
C)   1
D)   0.1
E)   Any choice would be equally effective.

Question 5

Sulfonamides are analogs of PABA and, as a result, they inhibit _____ synthesis.

Accepted Answer

A)   protein
B)   DNA
C)   RNA
D)   folic acid
E)   phospholipid

Question 6

The use of antibiotics in cattle feed leads to the development of antibiotic-resistant bacteria.

Accepted Answer

A) True 
 B)False

Question 7

Which antimicrobial does not inhibit cell wall synthesis?

Accepted Answer

A)   Gentamicin
B)   Vancomycin
C)   Cephalosporins
D)   Penicillins
E)   Carbapenems

Question 8

Organisms have a tendency to develop resistance to beta-lactams, and humans can develop allergic reactions to them. A drug that also targets the cell wall and can be used as an alternative is _______.

Accepted Answer

A)   tetracycline
B)   ?uoroquinolone
C)   streptomycin
D)   vancomycin
E)   chloramphenicol

Question 9

Which of the following is not a drug group used to treat fungal infections?

Accepted Answer

A)   Quinolones
B)   Macrolide polyene antibiotics
C)   Griseofulvin
D)   Synthetic azoles
E)   Flucytosine

Question 10

Drugs that target the plasma membrane are able to do so because _______.

Accepted Answer

A)   they are able to denature the membrane-associated proteins, creating pores thereby disrupting the integrity
B)   they target the phosphate group on the phospholipids, breaking down the bilayer
C)   they contain a lipid part that enables them to act as a detergent
D)   they act as enzymes to break down the phospholipids

Question 11

Which of the following phrases reﬂects an effective treatment of bioﬁlms?

Accepted Answer

A)   Add DNase to the antibiotics to disrupt extracellular debris
B)   Interrupt quorum-sensing pathways, preventing signaling between cells
C)   Pre-treat with newly-discovered antimicrobials before exposure to established drugs
D)   All of the choices are correct.

Question 12

Which group are the key drugs used to treat Hansen's disease (leprosy) ?

Accepted Answer

A)   Sulfonamides
B)   Sulfones
C)   Fluoroquinolones
D)   Polymyxins
E)   Streptomyces B

Question 13

A chemical that inhibits beta-lactamase enzymes is ______.

Accepted Answer

A)   synercid
B)   penicillinase
C)   aztreonam
D)   clavulanic acid
E)   imipenem

Question 14

Indwelling catheter bioﬁlm infections are more resistant to antibiotics than nonbioﬁlm infections.

Accepted Answer

A) True 
 B)False

Question 15

Antimicrobial drugs that inhibit folic acid synthesis work with no side effects because mammals must get folic acid from their diet.

Accepted Answer

A) True 
 B)False

Question 16

What antibiotic is mixed with neomycin and polymyxin to make an antibiotic ointment (Neosporin)  for superﬁcial skin infections?

Accepted Answer

A)   Vancomycin
B)   Bacitracin
C)   Chloramphenicol
D)   Streptomycin
E)   Clindamycin B

Question 17

Ampicillin, amoxicillin, mezlocillin, and penicillin G all have ______.

Accepted Answer

A)   a semisynthetic nature
B)   a beta-lactam ring
C)   resistance to the action of penicillinase
D)   an expanded spectrum of activity

Question 18

Mebendazole, thiabendazole, and ivermectin are drugs used to treat _______ infections.

Accepted Answer

A)   bacterial
B)   fungal
C)   protozoan
D)   helminthic
E)   viral

Question 19

Each of the following contributes to emerging drug resistance except _______.

Accepted Answer

A)   overuse of antibiotics
B)   improper use of antibiotics
C)   multiple drug therapy
D)   ingestion of antibiotics with animal feed
E)   addition of antibiotics to common household products

Question 20

The production of antibiotics by microbes evolved so that _______.

Accepted Answer

A)   bacteria and viruses could be eliminated
B)   diseases could be cured
C)   certain environments can be protected from pathogenic bacteria
D)   the growth of other organisms sharing their habitat was inhibited, thus giving them a selective advantage

Exam 12: Antimicrobial Treatment

Antimicrobials effective against a wide variety of microbial types are termed ______.

Correct Answer
verified

Which of the following is not a therapeutic beneﬁt of interferon?

Correct Answer
verified

Correct Answer
verified
C

A drug exhibiting which therapeutic index value would be the safest, most effective to use on a patient?

Correct Answer
verified

Sulfonamides are analogs of PABA and, as a result, they inhibit _____ synthesis.

Correct Answer
verified

The use of antibiotics in cattle feed leads to the development of antibiotic-resistant bacteria.

Correct Answer
verified

Which antimicrobial does not inhibit cell wall synthesis?

Correct Answer
verified

Organisms have a tendency to develop resistance to beta-lactams, and humans can develop allergic reactions to them. A drug that also targets the cell wall and can be used as an alternative is _______.

Correct Answer
verified

Which of the following is not a drug group used to treat fungal infections?

Correct Answer
verified

Drugs that target the plasma membrane are able to do so because _______.

Correct Answer
verified

Which of the following phrases reﬂects an effective treatment of bioﬁlms?

Correct Answer
verified

Which group are the key drugs used to treat Hansen's disease (leprosy) ?

Correct Answer
verified
B

A chemical that inhibits beta-lactamase enzymes is ______.

Correct Answer
verified

Indwelling catheter bioﬁlm infections are more resistant to antibiotics than nonbioﬁlm infections.

Correct Answer
verified

Antimicrobial drugs that inhibit folic acid synthesis work with no side effects because mammals must get folic acid from their diet.

Correct Answer
verified

What antibiotic is mixed with neomycin and polymyxin to make an antibiotic ointment (Neosporin) for superﬁcial skin infections?

Correct Answer
verified
B

Ampicillin, amoxicillin, mezlocillin, and penicillin G all have ______.

Correct Answer
verified

Mebendazole, thiabendazole, and ivermectin are drugs used to treat _______ infections.

Correct Answer
verified

Each of the following contributes to emerging drug resistance except _______.

Correct Answer
verified

The production of antibiotics by microbes evolved so that _______.

Correct Answer
verified

Exam 12: Antimicrobial Treatment

Antimicrobials effective against a wide variety of microbial types are termed ______.

Correct AnswerverifiedShow Answer

Which of the following is not a therapeutic beneﬁt of interferon?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedC

A drug exhibiting which therapeutic index value would be the safest, most effective to use on a patient?

Correct AnswerverifiedShow Answer

Sulfonamides are analogs of PABA and, as a result, they inhibit _____ synthesis.

Correct AnswerverifiedShow Answer

The use of antibiotics in cattle feed leads to the development of antibiotic-resistant bacteria.

Correct AnswerverifiedShow Answer

Which antimicrobial does not inhibit cell wall synthesis?

Correct AnswerverifiedShow Answer

Organisms have a tendency to develop resistance to beta-lactams, and humans can develop allergic reactions to them. A drug that also targets the cell wall and can be used as an alternative is _______.

Correct AnswerverifiedShow Answer

Which of the following is not a drug group used to treat fungal infections?

Correct AnswerverifiedShow Answer

Drugs that target the plasma membrane are able to do so because _______.

Correct AnswerverifiedShow Answer

Which of the following phrases reﬂects an effective treatment of bioﬁlms?

Correct AnswerverifiedShow Answer

Which group are the key drugs used to treat Hansen's disease (leprosy) ?

Correct AnswerverifiedB

A chemical that inhibits beta-lactamase enzymes is ______.

Correct AnswerverifiedShow Answer

Indwelling catheter bioﬁlm infections are more resistant to antibiotics than nonbioﬁlm infections.

Correct AnswerverifiedShow Answer

Antimicrobial drugs that inhibit folic acid synthesis work with no side effects because mammals must get folic acid from their diet.

Correct AnswerverifiedShow Answer

What antibiotic is mixed with neomycin and polymyxin to make an antibiotic ointment (Neosporin) for superﬁcial skin infections?

Correct AnswerverifiedB

Ampicillin, amoxicillin, mezlocillin, and penicillin G all have ______.

Correct AnswerverifiedShow Answer

Mebendazole, thiabendazole, and ivermectin are drugs used to treat _______ infections.

Correct AnswerverifiedShow Answer

Each of the following contributes to emerging drug resistance except _______.

Correct AnswerverifiedShow Answer

The production of antibiotics by microbes evolved so that _______.

Correct AnswerverifiedShow Answer

Correct Answer
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Correct Answer
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Correct Answer
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C

Correct Answer
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B

Correct Answer
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B

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