Question 1

What is the relationship between cannabis and the immune system?

Accepted Answer

A)   Cannibis may increase the risk of auto-immunity and the risk of infection.
B)   Cannibis may increase the risk of auto-immunity and decrease risk of infection.
C)   Cannibis may decrease risk of auto-immunity and increase the risk of infection.
D)   Cannibis may decrease the risk of auto-immunity and decrease the risk of infection.

Question 2

Compared with the negative subjective effects caused by Δ9-THC, the negative subjective effects of cannabis are ____.

Accepted Answer

A)   fewer in number
B)   greater in number
C)   the same
D)   unpredictable

Question 3

What is cannabis's key psychoactive ingredient?

Accepted Answer

A)   Δ9-THC
B)   Δ8-THC
C)   cannabidiol
D)   cannabinol

Question 4

According to a study by Georgotas and Zeidenberg (1979) , the sudden cessation of chronic cannabis use can lead to ____.

Accepted Answer

A)   seizure
B)   irritability
C)   stroke
D)   increased appetite

Question 5

How do anandaminde and 2-AG differ from most other neurotransmitters?

Accepted Answer

A)   They are not metabolized.
B)   They are not stored in vesicles.
C)   They do not bind to a receptor.
D)   They are synthesized in the nucleus.

Question 6

Many studies find mild memory deficits occurring after acute administration with cannabis or Δ9-THC. For example, Weil and colleagues (1968)  found that cannabis use ____.

Accepted Answer

A)   increased short-term memory while decreasing long-term memory
B)   decreased short-term memory while increasing long-term memory
C)   impaired memory performance while failing to impair attention performance
D)   impaired attention performance while failing to impair memory performance

Question 7

Dr. Daly studies how endocannabinoid neurotransmitters interact with neuronal receptors. What neurotransmitters is she likely to study?

Accepted Answer

A)   dronabinol and 2-AG
B)   dronabinol and 15d-PG2
C)   anandamide and 2-AG
D)   anandamide and 15d-PG2

Question 8

Herbal marijuana alternatives are ____.

Accepted Answer

A)   laboratory-synthesized cannabinoid receptor agonists
B)   cannabis plants that have been modified to no longer contain Δ9-THC
C)   other psychoactive plants that are typically stronger than cannabis
D)   safer natural alternatives to cannabis

Question 9

Δ9-THC exhibits high lipid solubility. How does this impact its effects?

Accepted Answer

A)   This leads to slow distribution in tissues.
B)   This decreases its elimination time.
C)   Δ9-THC becomes sequestered in fat, leading to long-term pharmacological actions
D)   Δ9-THC becomes sequestered in fat, making it less effective

Question 10

The use of cannabis in modern medicine largely began from the efforts of ____.

Accepted Answer

A)   Shen-Nung
B)   al-Hasan ibn al-Sabbah
C)   William O'Shaughnessy
D)   Marco Polo

Question 11

Research associate Dr. Blake would like to prevent the breakdown of anandamide into inactive compounds. Which enzyme should he target?

Accepted Answer

A)   NAPE phospholipase D
B)   sn-1-diacyglycerole lipase
C)   Monoacylglycerol lipase
D)   FAAH

Question 12

What role have animal models played in supporting or refuting cannabis's effect on appetite?

Accepted Answer

A)   Animal models show that the "munchies" are not a real phenomenon.
B)   Animal models support that the "munchies" are a real phenomenon.
C)   Animal models have not been useful in evaluating the "munchie" response.
D)   Animal models show variable "munchie" "stuffed" responses.

Question 13

Outside the brain, CB1 receptors can be found in the heart, kidneys, liver, spleen, and ____.

Accepted Answer

A)   muscles
B)   pancreas
C)   skin
D)   intestines

Question 14

According to a study by Georgotas and Zeidenberg (1979) , participants required ____.

Accepted Answer

A)   the same amount of cannabis throughout the study
B)   more cannabis administration as the study progressed
C)   less cannabis administration as the study progressed
D)   more or less cannabis administration depending on whether they were male or female

Question 15

Small hairlike structures with glands that release a resin containing a number of phytocannabinoids are called ____.

Accepted Answer

A)   panicles
B)   trichomes
C)   racemes
D)   calyxes

Question 16

The United States first criminalized cannabis for nonmedical purposes in ____.

Accepted Answer

A)   1927
B)   1937
C)   1947
D)   1957

Question 17

Describe two studies that explore the subjective effects of cannabis in humans. Discuss how the experiments were performed, provide an analysis of the results, and report on the significance of the findings.

Accepted Answer

To carefully assess the subjective effec...

Question 18

Today, many clinicians recognize a series of potential withdrawal symptoms from cannabis, which Beseler and Hasin (2010)  describes as consisting of, in part, ____.

Accepted Answer

A)   aggression
B)   amotivation
C)   hallucinations
D)   delusions

Question 19

Cancer patient Janice is prescribed a cannabinoid medication that consists of a one-to-one ratio of cannabidiol and Δ9-THC. What medication was she prescribed?

Accepted Answer

A)   Anandamide
B)   WIN55212-2
C)   Sativex
D)   Marinol

Question 20

What were the findings of a study by Foltin and colleagues (1990)  regarding cannabis use and motivation?

Accepted Answer

A)   Cannabis users chose effortless tasks, showing a loss of motivation.
B)   The use of cannabis had no effect on whether a participant chose an effortful or effortless task.
C)   Cannabis users chose tasks requiring more effort perhaps because these tasks seemed less effortful.
D)   Although cannabis users chose more effortful tasks, they chose to complete less tasks overall than non-cannabis users.

Exam 11: Cannabinoids

According to a study by Georgotas and Zeidenberg (1979) , participants required ____.

Correct AnswerverifiedShow Answer

Compared with the negative subjective effects caused by Δ9-THC, the negative subjective effects of cannabis are ____.

Correct AnswerverifiedShow Answer

What is cannabis's key psychoactive ingredient?

Correct AnswerverifiedShow Answer

What role have animal models played in supporting or refuting cannabis's effect on appetite?

Correct AnswerverifiedShow Answer

According to a study by Georgotas and Zeidenberg (1979) , the sudden cessation of chronic cannabis use can lead to ____.

Correct AnswerverifiedShow Answer

Δ9-THC exhibits high lipid solubility. How does this impact its effects?

Correct AnswerverifiedShow Answer

How do anandaminde and 2-AG differ from most other neurotransmitters?

Correct AnswerverifiedShow Answer

The use of cannabis in modern medicine largely began from the efforts of ____.

Correct AnswerverifiedShow Answer

Dr. Daly studies how endocannabinoid neurotransmitters interact with neuronal receptors. What neurotransmitters is she likely to study?

Correct AnswerverifiedShow Answer

Outside the brain, CB1 receptors can be found in the heart, kidneys, liver, spleen, and ____.

Correct AnswerverifiedShow Answer

What were the findings of a study by Foltin and colleagues (1990) regarding cannabis use and motivation?

Correct AnswerverifiedShow Answer

Describe two studies that explore the subjective effects of cannabis in humans. Discuss how the experiments were performed, provide an analysis of the results, and report on the significance of the findings.

Correct AnswerverifiedTo carefully assess the subjective effec...View AnswerShow Answer

Cancer patient Janice is prescribed a cannabinoid medication that consists of a one-to-one ratio of cannabidiol and Δ9-THC. What medication was she prescribed?

Correct AnswerverifiedShow Answer

The United States first criminalized cannabis for nonmedical purposes in ____.

Correct AnswerverifiedShow Answer

Small hairlike structures with glands that release a resin containing a number of phytocannabinoids are called ____.

Correct AnswerverifiedShow Answer

Many studies find mild memory deficits occurring after acute administration with cannabis or Δ9-THC. For example, Weil and colleagues (1968) found that cannabis use ____.

Correct AnswerverifiedShow Answer

Today, many clinicians recognize a series of potential withdrawal symptoms from cannabis, which Beseler and Hasin (2010) describes as consisting of, in part, ____.

Correct AnswerverifiedShow Answer

Herbal marijuana alternatives are ____.

Correct AnswerverifiedShow Answer

Research associate Dr. Blake would like to prevent the breakdown of anandamide into inactive compounds. Which enzyme should he target?

Correct AnswerverifiedShow Answer

What is the relationship between cannabis and the immune system?

Correct AnswerverifiedShow Answer

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Compared with the negative subjective effects caused by Δ⁹-THC, the negative subjective effects of cannabis are ____.

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Δ⁹-THC exhibits high lipid solubility. How does this impact its effects?

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Outside the brain, CB₁ receptors can be found in the heart, kidneys, liver, spleen, and ____.

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To carefully assess the subjective effec...
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Cancer patient Janice is prescribed a cannabinoid medication that consists of a one-to-one ratio of cannabidiol and Δ⁹-THC. What medication was she prescribed?

Correct Answer
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Many studies find mild memory deficits occurring after acute administration with cannabis or Δ⁹-THC. For example, Weil and colleagues (1968) found that cannabis use ____.

Correct Answer
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