Question 1

Aspirin _______________.

Accepted Answer

A)  induced damage even at low doses manifests itself quickly
B)  in large doses can alter the acid-base balance
C)  should be taken with plenty of fluids but not with food
D)  is the preferred drug for children with viral infections

Question 2

Which of the following is recommended when taking both an NSAID for inflammation and low-dose aspirin for cardiac protection?

Accepted Answer

A)  The NSAID should be given 2 hours before the aspirin.
B)  The aspirin should be given 2 hours before the NSAID.
C)  The aspirin should be given on one day and the NSAID on the next day.
D)  Dosing with aspirin and NSAIDs is contraindicated because of increased GI bleeding. B

Question 3

The hallmarks of an early inflammation are _______________.

Accepted Answer

A)  redness and pain
B)  swelling and warmth
C)  tissue destruction
D)  All of the above

Question 4

Which one of the following statements concerning cyclooxygenase or COX is correct?

Accepted Answer

A)  COX 1 is involved in the production of some helpful prostaglandins.
B)  COX 2 is induced with injury.
C)  COX 3 may be present in the brain.
D)  All of the above

Question 5

Which one of the following is not a typical adverse reaction of the opioids?

Accepted Answer

A)  Mydriasis
B)  Constipation
C)  Nausea and vomiting
D)  Pruritis

Question 6

Which one of the following statements is true?

Accepted Answer

A)  Neuropathic pain can effectively be treated with antidepressants.
B)  A fixed dosing schedule with opioids seems to be superior to giving medication on an as needed administration for cancer pain.
C)  Cox-2 inhibitors can be used for post-op pain especially in a cardiac patient.
D)  OTC aspirin and ibuprofen are safer than other prescription NSAIDs.

Question 7

A patient taking aspirin or NSAIDs should be regularly monitored for which of the following?

Accepted Answer

A)  Hypotension
B)  Menstrual cramps
C)  Petechiae
D)  Elevated liver transaminases C

Question 8

A patient who takes opioids over a long period of time may need which of the following drugs?

Accepted Answer

A)  Laxative
B)  Anticholinergic
C)  Adrenergic agonist
D)  Antidiarrheal

Question 9

The action of prostaglandins includes which of the following?

Accepted Answer

A)  uterine relaxation
B)  reduction in body temperature
C)  stabilization of gastric mucosa
D)  vasodilatation of renal blood supply

Question 10

Which one of the following is not a vasodilating,inflammatory mediator?

Accepted Answer

A)  Certain prostaglandins
B)  Bradykinin
C)  Histamine
D)  Thromboxane

Question 11

Which one of the following statements regarding NSAIDs is true?

Accepted Answer

A)  They reduce pain and allow more rigorous training to be performed to obtain better muscle strength.
B)  They may produce low BP in some individuals.
C)  They are useful in reducing pain and inflammation but caution should be applied when used in patients with HTN.
D)  They have replaced acetaminophen as the drug of choice in the treatment of osteoarthritic knees. C

Question 12

Which of the following statements is true?

Accepted Answer

A)  Morphine is metabolized to the inactive metabolite morphine-6-glucuronide.
B)  Morphine and codeine can be given together for stronger pain relief.
C)  Codeine is converted to morphine in the body.
D)  Strong opioids bind strongly to kappa receptors.

Question 13

Recent research on antiinflammatory drugs suggests that the main disadvantage of COX-2 inhibitors compared to the nonselective agents is increased ___________.

Accepted Answer

A)  Gastric bleeding
B)  Cardiac events
C)  Sedation
D)  Dehydration

Question 14

A patient in ambulation training is on warfarin after a stroke.He is developing some tendonitis and is asking your opinion on which aspirin-type drug is better for pain,Aleve or Motrin.Your best response should be which of the following?

Accepted Answer

A)  Inform the patient of the potential drug interactions with anticoagulants.
B)  Inform the patient to administer a 650-mg dose of aspirin.
C)  Explain that tendonitis is an expected outcome of therapy and it will improve shortly with more therapy.
D)  Suggest that the patient take ibuprofen instead.

Question 15

NSAIDs drugs _______________.

Accepted Answer

A)  block the conversion of arachadonic acid to prostaglandin formation
B)  are antiinflammatory at lower and analgesic at higher doses
C)  differ markedly in efficacy
D)  differ significantly in their adverse reactions

Question 16

Pain can be classified as _______________.

Accepted Answer

A)  nociceptive pain arising from nerve damage
B)  neuropathic pain arising from injury
C)  psychogenic pain arising from a psychological disorder
D)  all are correct

Question 17

Death due to an overdose of morphine is due to _______________.

Accepted Answer

A)  respiratory depression
B)  ventricular fibrillation
C)  bronchoconstriction
D)  All of the above

Question 18

NSAIDs drugs can be divided into _______________.

Accepted Answer

A)  COX 1 and 2 inhibitors
B)  COX 2 inhibitors
C)  COX 3 inhibitors
D)  All of the above

Question 19

Which of the following substances inhibits pain impulses?

Accepted Answer

A)  substance P
B)  Serotonin
C)  prostaglandins
D)  glutamate

Question 20

Which of the following enzymes are released from synoviocytes with tissue injury?

Accepted Answer

A)  COX-1
B)  COX-2
C)  COX-3
D)  Lipoxygenase

Exam 11: Drugs for the Treatment of Pain and Inflammation

Aspirin _______________.

Correct AnswerverifiedShow Answer

Which of the following is recommended when taking both an NSAID for inflammation and low-dose aspirin for cardiac protection?

Correct AnswerverifiedB

The hallmarks of an early inflammation are _______________.

Correct AnswerverifiedShow Answer

Which one of the following statements concerning cyclooxygenase or COX is correct?

Correct AnswerverifiedShow Answer

Which one of the following is not a typical adverse reaction of the opioids?

Correct AnswerverifiedShow Answer

Which one of the following statements is true?

Correct AnswerverifiedShow Answer

A patient taking aspirin or NSAIDs should be regularly monitored for which of the following?

Correct AnswerverifiedC

A patient who takes opioids over a long period of time may need which of the following drugs?

Correct AnswerverifiedShow Answer

The action of prostaglandins includes which of the following?

Correct AnswerverifiedShow Answer

Which one of the following is not a vasodilating,inflammatory mediator?

Correct AnswerverifiedShow Answer

Which one of the following statements regarding NSAIDs is true?

Correct AnswerverifiedC

Which of the following statements is true?

Correct AnswerverifiedShow Answer

Recent research on antiinflammatory drugs suggests that the main disadvantage of COX-2 inhibitors compared to the nonselective agents is increased ___________.

Correct AnswerverifiedShow Answer

A patient in ambulation training is on warfarin after a stroke.He is developing some tendonitis and is asking your opinion on which aspirin-type drug is better for pain,Aleve or Motrin.Your best response should be which of the following?

Correct AnswerverifiedShow Answer

NSAIDs drugs _______________.

Correct AnswerverifiedShow Answer

Pain can be classified as _______________.

Correct AnswerverifiedShow Answer

Death due to an overdose of morphine is due to _______________.

Correct AnswerverifiedShow Answer

NSAIDs drugs can be divided into _______________.

Correct AnswerverifiedShow Answer

Which of the following substances inhibits pain impulses?

Correct AnswerverifiedShow Answer

Which of the following enzymes are released from synoviocytes with tissue injury?

Correct AnswerverifiedShow Answer

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C

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