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Emphysema results from destruction of alveolar walls and capillaries, which is due to


A) release of proteolytic enzymes from immune cells.
B) air trapping with resultant excessive alveolar pressure.
C) excessive a1-antitrypsin.
D) autoantibodies against pulmonary basement membrane.

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The increased anterior-posterior chest diameter associated with obstructive lung disease is caused by


A) increased pulmonary blood flow.
B) increased expiratory flow rates.
C) increased residual lung volumes.
D) decreased chest wall compliance.

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To best prevent emphysema, a patient is instructed to stop smoking since cigarette smoke


A) impairs alpha1-antitrypsin, allowing elastase to predominate.
B) paralyzes the cilia, causing impaired mucociliary clearance.
C) predisposes to respiratory infections.
D) introduces carcinogens into the lungs.

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An acute asthma attack is associated with


A) bronchoconstriction.
B) bronchial mucosal edema.
C) hypersecretion of mucus.
D) alveolar collapse.
E) hypoxemia.

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Characteristics of asthma include


A) chronic inflammatory disorder.
B) airway hyperresponsiveness.
C) alveolar collapse.
D) genetic susceptibility.
E) airway remodeling.

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Which complication of asthma is life threatening?


A) Exercise-induced asthma
B) Late phase response
C) Status asthmaticus
D) Mast cell degranulation

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After evaluation, a child's asthma is characterized as "extrinsic." This means that the asthma is


A) of unknown pathogenesis.
B) associated with specific allergic triggers.
C) associated with respiratory infections.
D) induced by psychological factors (stress) .

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Cystic fibrosis is associated with


A) asthma.
B) chronic bronchitis.
C) bronchiectasis.
D) emphysema.

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Which assessment would support a diagnosis of type A COPD rather than type B COPD


A) Copious sputum, dyspnea, cor pulmonale
B) Noisy breath sounds, fatigue, high PaO₂, overweight
C) Normal PaO₂, scant sputum, accessory muscle use, barrel chest
D) Barrel chest, productive cough, cyanosis, very decreased PaO₂

Correct Answer

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