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The progressive shortening of telomeres in DNA correlates with cell senescence.

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________ attaches DNA sequences at the ends of eukaryotic chromosomes.


A) Polymerase
B) Ligase
C) Telomerase
D) Topoisomerase
E) Primase

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C

During the DNA replication process, which of the following organisms would have the fewest origins of replication per cell?


A) a rapidly dividing Streptococcus bacterium
B) a yeast cell
C) a human
D) a young oak tree
E) a fruit fly

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A

All of the following nucleotide bases are pyrimidines EXCEPT


A) adenine.
B) thymine.
C) cytosine.
D) uracil.
E) cytosine and thymine.

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Unlike the leading strand, ______________ are made in replicating the lagging strand of DNA.


A) primers
B) nucleases
C) Okazaki fragments
D) pyrophosphates
E) DNA polymerases

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Where would one expect to find the most telomerase?


A) male germ cells that give rise to gametes
B) skin cells from a 60-year-old individual
C) skin cells from a 2-year-old individual
D) a nerve cell from a 60-year-old individual
E) a nerve cell from a 2-year-old individual

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Which of the following does NOT belong with the others?


A) replication fork
B) single-stranded binding proteins
C) DNA ligase
D) topoisomerase
E) helicase

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C

What is the complement DNA strand to 5?-ATTCGGTGA-3??


A) 5?-TAAGCCACT-3?
B) 3?-CGGATTGTC-5?
C) 5?-CGGATTGTC-3?
D) 3?-TAAGCCACT-5?
E) 3?-ATTCGGTGA-5

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Which of the following statements about telomeres is INCORRECT?


A) Telomeres are produced by telomerase.
B) Telomeres are found at the ends of DNA.
C) Telomeres are short repeat sequences.
D) Telomeres would predominate more in cells of older than younger individuals.
E) Telomeres are crucial to the viability of a cell that replicates often.

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Studies by Avery, MacLeod, and McCarty with different strains of bacteria and those by Hershey and Chase with T2 bacteriophage determined that proteins are highly complex molecules that form the genetic material for bacteria and viruses.

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Which of the following scientist-discoveries is mismatched?


A) Watson, Crick, Wilkins, and Franklin-DNA structure
B) Avery, MacLeod, and McCarty-DNA is the genetic material
C) Meselson and Stahl-mechanism of DNA replication
D) Griffith-chromosomes
E) Hershey and Chase-DNA is the genetic material of bacteriophage

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The protein of T2 bacteriophage is labeled with 35S and the DNA with 32P. Where would one detect most of the 32P if the T2 bacteriophage were allowed to infect the bacteria?


A) on the phage coat surrounding the T2 bacteriophage
B) on the membrane of the infected bacteria
C) inside the T2 bacteriophage capsid
D) inside the infected bacteria
E) The 32P would be equally distributed within the T2 bacteriophage and infected bacteria.

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