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Exam 22: Fatty Acid Catabolism

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Question 1

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Which of the following steps is NOT a part of the sequence of events for activation of the release of fatty acids from adipose cells?

A) triacylglycerol lipase inactivation
B) adenylyl cyclase activation
C) cAMP production
D) hormone binding to the receptor

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Question 2

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Which of the following is NOT a use for acetyl-CoA,a product of b-oxidation?

A) synthesis of ketone bodies
B) synthesis of amino acids
C) catabolism in the TCA cycle
D) synthesis of glucose

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Question 3

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Which of the following TCA cycle intermediates is propionyl-CoA ultimately converted to?

How many times must the ?-oxidation cycle be repeated for the complete oxidation of a saturated fatty acid with 16 carbons?

Which of the following classes of enzymes does enoyl-CoA hydratase belong to?

Which of the following lipid components are produced in the duodenum by the enzyme pancreatic lipase during lipid digestion?

How many NADH are generated from the complete oxidation of palmitoyl-CoA to CO₂?

Which of the following sequences of metabolic reactions is analogous to the first 3 reactions of ?-oxidation of saturated fatty acids?

Which of the following is NOT involved with the transport of fatty acyl groups from the cytosol to the matrix?

Which of the following are the 3 most common ketone bodies?

Which of the following series correctly describes the conversion of a fatty acid to CO₂?

Which of the following cellular locations is the site for where fatty acids are condensed with coenzyme A to form acyl-CoA for β-oxidation?

The first oxidation in the β-oxidation of saturated fatty acids is catalyzed by acyl-CoA dehydrogenase.Which of the following chemical conversions does it catalyze?

How many NAD⁺ are reduced in the b-oxidation of stearoyl-CoA to form 9 molecules of acetyl-CoA?

Where are ketone bodies synthesized?

During ?-oxidation of certain unsaturated fatty acids,cis-?³-fatty acyl-CoAs are formed that must be converted to trans-?²-fatty acyl-CoAs.Which of the following enzymes converts them to trans-?²-fatty acyl-CoAs?

How do ketone body carbons enter the major metabolic pathways of the cells?

Which of the following hormones does NOT cause fatty acid mobilization in adipose cells?

In ketone body biosynthesis,the HMG-CoA lyase reaction is mechanistically the reverse of the first half of the reaction catalyzed by a particular TCA enzyme.Which of the following TCA enzymes does it resemble?

Which of the following tissues stores triacylglycerols?