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How many protons are translocated across the membrane by complex I for every pair of electrons that are passed from NADH to QH2?


A) 1
B) 2
C) 3
D) 4
E) 5

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A muscle cell from an alligator jaw contains more mitochondria than a wing muscle of a migrating bird such as a goose.

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Iron sulfur clusters (Fs-S) that can accept or donate one electron are found in which complexes of the electron transport chain?


A) I
B) II and III
C) I,II and III
D) I,II,III and IV

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The chemiosmotic theory is a concept that ________.


A) the transport of Na+ and K+ across cell membranes is by active transport
B) explains how transport by facilitated diffusion reaches a saturation limit
C) explains the blood-brain barrier
D) a proton gradient drives the formation of ATP

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The ultimate electron acceptor from complex II is ________.


A) Q
B) QH2
C) cytochrome c
D) O2
E) FMN

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The human mitochondrial genome contains genes for all of the complexes necessary for electron transport and oxidative phosphorylation.

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Superoxide dismutase protects cells from damage caused by ________.


A) ∙O²-
B) O3²-
C) H₂O₂
D) H₃O+

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According to the binding change mechanism,the (alpha3 beta3 ) oligomer of ATP synthase containing 3 catalytic sites can each have ________ different conformations.


A) 2
B) 3
C) 6
D) 9

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Complex I contains a porin protein subunit that transports H+ across the inner mitochondrial membrane.

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Which is a component of complex I?


A) FAD
B) FMN
C) Q
D) TPP

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Membrane- associated electron transport complexes I and II are linked by ubiquinone (Q)while complexes II and IV are linked by cytochrome c.

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Which statement is not true about the transport of ATP across the inner mitochondrial membrane on its way to the cytosol?


A) It is accomplished by adenine nucleotide translocase.
B) The same enzyme that transports ATP also transport ADP in the opposite direction.
C) It is complexed with Mg2+ to reduce the draw on the electrical part of the protonmotive force.
D) The transport causes the loss of a net charge of -1 in the matrix.

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The synthesis of one molecule of ATP from ADP requires ________ to be translocated across the inner mitochondrial membrane.


A) one proton
B) three protons
C) hundreds of protons
D) 1 mole of protons

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Mitochondrial electron transport and ATP formation are interdependent.

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The numbers of mitochondria in cells is closely associated with cell function.

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ATP directly provides the energy to transport protons across the inner membrane from the matrix to the intermembrane space of mitochondria.

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Which of the following substances can freely pass through the inner mitochondrial membrane?


A) H+
B) Acetate
C) CO2
D) ATP

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What is the Gibbs free energy change,△G,across a membrane with a pH difference of 0.50 and a membrane potential of -0.10 V at 310 K? (R = 8.315 J K-1 mol-1;F = 96,485 J V-1 mol-1)


A) -6.85 kJ mol-1
B) -12.6 kJ mol-1
C) 38.6 kJ mol-1
D) 57.9 kJ mol-1

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The P/O ratio is independent of whether electrons originate from complex I or complex II.

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A lipid-soluble cofactor that can diffuse freely in the membrane of the electron transport chain and carry electrons across the membrane is ________.


A) ubiquinone (Q)
B) Fe-S
C) cytochrome c
D) FADH₂

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