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The Darwinian fitness of an individual is measured most directly by


A) the number of its offspring that survive to reproduce.
B) the number of "good genes" it possesses.
C) the number of mates it attracts.
D) its physical strength.
E) how long it lives.

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If the original finches that had been blown over to the Galapagos from South America had already been genetically different from the parental population of South American finches, even before adapting to the Galapagos, this would have been an example of


A) genetic drift.
B) bottleneck effect.
C) founder's effect.
D) all three of these
E) both A and C

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About which of these did Darwin have a poor understanding?


A) that individuals in a population exhibit a good deal of variation
B) that much of the variation between individuals in a population is inherited
C) the factors that cause individuals in populations to struggle for survival
D) the sources of genetic variations among individuals
E) how a beneficial trait becomes more common in a population over the course of generations

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If neutral variation is truly "neutral," then it should have no effect on


A) nucleotide diversity.
B) average heterozygosity.
C) our ability to measure the rate of evolution.
D) relative fitness.
E) gene diversity.

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A certain species of land snail exists as either a cream color or a solid brown color. Intermediate individuals are relatively rare. Which of the following terms best describes this?


A) artificial selection
B) directional selection
C) stabilizing selection
D) disruptive selection
E) sexual selection

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In the wild, male house finches (Carpodus mexicanus) vary considerably in the amount of red pigmentation in their head and throat feathers, with colors ranging from pale yellow to bright red. These colors come from carotenoid pigments that are found in the birds' diets; no vertebrates are known to synthesize carotenoid pigments. Thus, the brighter red the male's feathers are, the more successful he has been at acquiring the red carotenoid pigment by his food-gathering efforts (all other factors being equal) . -The situation as described in the paragraph above should select most directly against males that


A) are unable to distinguish food items that are red from those of other colors.
B) are older, but still healthy.
C) are capable of defending only moderately sized territories.
D) have slightly lower levels of testosterone during breeding season than have other males.
E) have no prior experience courting female house finches.

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A trend toward the decrease in the size of plants on the slopes of mountains as altitudes increase is an example of


A) a cline.
B) a bottleneck.
C) relative fitness.
D) genetic drift.
E) geographic variation.

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Arrange the following from most general (i.e., most inclusive) to most specific (i.e., least inclusive) : 1. Natural selection 2) Microevolution 3) Intrasexual selection 4) Evolution 5) Sexual selection


A) 4, 1, 2, 3, 5
B) 4, 2, 1, 3, 5
C) 4, 2, 1, 5, 3
D) 1, 4, 2, 5, 3
E) 1, 2, 4, 5, 3

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Adult male humans generally have deeper voices than do adult female humans, as the direct result of higher levels of testosterone causing growth of the larynx. -Which addition to the information in the paragraph above would make more than one of the answers listed in the previous question correct?


A) If larynx size was also affected by the amount the larynx was used (i.e., the amount of vocalization) .
B) If males prefer to mate with females possessing higher voices.
C) If females killed female offspring whose voices were too deep.
D) If the trend described above was seen in the fossil record of only one species of ape.

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Which statement about variation is True?


A) All phenotypic variation is the result of genotypic variation.
B) All genetic variation produces phenotypic variation.
C) All nucleotide variability results in neutral variation.
D) All new alleles are the result of nucleotide variability.
E) All geographic variation results from the existence of clines.

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Sparrows with average-sized wings survive severe storms better than those with longer or shorter wings, illustrating


A) the bottleneck effect.
B) stabilizing selection.
C) frequency-dependent selection.
D) neutral variation.
E) disruptive selection.

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In the wild, male house finches (Carpodus mexicanus) vary considerably in the amount of red pigmentation in their head and throat feathers, with colors ranging from pale yellow to bright red. These colors come from carotenoid pigments that are found in the birds' diets; no vertebrates are known to synthesize carotenoid pigments. Thus, the brighter red the male's feathers are, the more successful he has been at acquiring the red carotenoid pigment by his food-gathering efforts (all other factors being equal) . -During breeding season, one should expect female house finches to prefer to mate with males with the brightest red feathers. Which of the following is True of this situation?


A) Alleles that promote more efficient acquisition of carotenoid-containing foods by males should increase over the course of generations.
B) Alleles that promote more effective deposition of carotenoid pigments in the feathers of males should increase over the course of generations.
C) There should be directional selection for bright red feathers in males.
D) All three of these.
E) Only B and C.

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Use the following information to answer the questions below. HIV's genome of RNA includes code for reverse transcriptase (RT) , an enzyme that acts early in infection to synthesize a DNA genome off of an RNA template. The HIV genome also codes for protease (PR) , an enzyme that acts later in infection by cutting long viral polyproteins into smaller, functional proteins. Both RT and PR represent potential targets for antiretroviral drugs. Drugs called nucleoside analogs (NA) act against RT, whereas drugs called protease inhibitors (PI) act against PR. -Within the body of an HIV-infected individual who is being treated with a single NA, and whose HIV particles are currently vulnerable to this NA, which of these situations can increase the virus' relative fitness? 1) mutations resulting in RTs with decreased rates of nucleotide mismatch 2) mutations resulting in RTs with increased rates of nucleotide mismatch 3) mutations resulting in RTs that have proofreading capability


A) 1 only
B) 2 only
C) 3 only
D) 1 and 3
E) 2 and 3

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There are 40 individuals in population 1, all of which have genotype A1A1, and there are 25 individuals in population 2, all of genotype A2A2. Assume that these populations are located far from one another and that their environmental conditions are very similar. Based on the information given here, the observed genetic variation is mostly likely an example of


A) genetic drift.
B) gene flow.
C) disruptive selection.
D) discrete variation.
E) directional selection.

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Use the following information to answer the questions below. A large population of laboratory animals has been allowed to breed randomly for a number of generations. After several generations, 25% of the animals display a recessive trait (aa) , the same percentage as at the beginning of the breeding program. The rest of the animals show the dominant phenotype, with heterozygotes indistinguishable from the homozygous dominants. -In a Hardy-Weinberg population with two alleles, A and a, that are in equilibrium, the frequency of allele a is 0.2. What is the frequency of individuals with Aa genotype?


A) 0.20
B) 0.32
C) 0.42
D) 0.80
E) Genotype frequency cannot be determined from the information provided.

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Rank the following 1-base point mutations (from most likely to least likely) with respect to their likelihood of affecting the structure of the corresponding polypeptide: 1. insertion mutation deep within an intron 2) substitution mutation at the 3rd position of an exonic codon 3) substitution mutation at the 2nd position of an exonic codon 4) deletion mutation within the first exon of the gene


A) 1, 2, 3, 4
B) 4, 3, 2, 1
C) 2, 1, 4, 3
D) 3, 1, 4, 2
E) 2, 3, 1, 4

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Adult male humans generally have deeper voices than do adult female humans, as the direct result of higher levels of testosterone causing growth of the larynx. -If the fossil records of apes and humans alike show a trend toward decreasing larynx size in adult females, and increasing larynx size in adult males, then


A) sexual dimorphism was developing over time in these species.
B) intrasexual selection seems to have occurred.
C) the "good genes" hypothesis was refuted by these data.
D) stabilizing selection was occurring in these species concerning larynx size.
E) selection was acting more directly upon genotype than upon phenotype.

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Natural selection is most nearly the same as


A) diploidy.
B) gene flow.
C) genetic drift.
D) non-random mating.
E) differential reproductive success.

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Use the following information to answer the questions below. In a hypothetical population of 1,000 people, tests of blood-type genes show that 160 have the genotype AA, 480 have the genotype AB, and 360 have the genotype BB. -If there are 4,000 children born to this generation, how many would be expected to have AB blood under the conditions of Hardy-Weinberg equilibrium?


A) 100
B) 960
C) 1,920
D) 2,000
E) 2,400

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There are those who claim that the theory of evolution cannot be True because the apes, which are supposed to be closely related to humans, do not likewise share the same large brains, capacity for complicated speech, and tool-making capability. They reason that if these features are generally beneficial, then the apes should have evolved them as well. Which of these provides the best argument against this misconception?


A) Advantageous alleles do not arise on demand.
B) A population's evolution is limited by historical constraints.
C) Adaptations are often compromises.
D) Evolution can be influenced by environmental change.

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