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It is widely believed that damage to the hippocampus is the major factor in the difficulties that medial temporal lobe amnesics have in recognizing objects.Why? What does relevant research on monkeys and rats suggest?

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40% for describing the evidenc...

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The human medial temporal lobe includes the


A) hippocampus.
B) amygdala.
C) medial temporal cortex.
D) CA1 subfield.
E) all of the above

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H.M.was


A) a famous neuropsychologist.
B) a person who had epilepsy.
C) an Egyptian.
D) a famous physiological psychologist.
E) a sad product of prefrontal lobotomy.

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Many __________ cells are located in hippocampus,whereas many grid cells are located in the entorhinal cortex.

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The brain operation performed on H.M.was a


A) unilateral temporal lobectomy.
B) bilateral prefrontal lobotomy.
C) bilateral temporal lobotomy.
D) bilateral medial temporal lobectomy.
E) none of the above

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The delayed nonmatching-to-sample test is a good measure of __________ long-term object-recognition memory in both rats and monkeys.

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Hippocampal lesions in rats reliably disrupt the performance of tasks that involve memory for


A) Pavlovian conditioning.
B) time.
C) spatial locations.
D) instrumental conditioning.
E) objects.

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Discuss medial temporal lobe amnesia,emphasizing the cases of H.M.and R.B.What have we learned from the study of this disorder?

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25% for discussing H.M.
25% fo...

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The induction of LTP at glutaminergic synapses appears to require


A) the depolarization of the postsynaptic neuron.
B) the depolarization of the presynaptic neuron.
C) an influx of calcium ions into the postsynaptic neuron.
D) both B and C
E) both A and C

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In an innovative series of experiments,Squire and his colleagues assessed the retrograde amnesia of patients following ECT.They assessed the patients' memory for television shows that


A) had played for more than 5 years.
B) had played for more than 3 years.
C) were currently playing during the experiment.
D) had played for only one season.
E) were first shown in other countries.

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Which of the following patients suffered ischemia-produced hippocampal damage?


A) H.M.
B) R.B.
C) S.B.
D) K.C.
E) N.A.

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The hippocampus appears to play a special role in memory for


A) spatial locations.
B) sounds.
C) names.
D) faces
E) odors.

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The mediodorsal nuclei,which are often damaged in cases of Korsakoff's amnesia,are nuclei of the


A) thalamus.
B) hypothalamus.
C) hippocampus.
D) cerebellum.
E) mammillary bodies.

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One of the major turning points in the study of the neuropsychology of memory was the year H.M.had his operation:


A) 1923.
B) 1934.
C) 1953.
D) 1983.
E) 1991.

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Dysfunction in the brains of Alzheimer's patients is often apparent in the


A) medial temporal lobe structures.
B) basal forebrain.
C) prefrontal cortex.
D) all of the above
E) none of the above

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Explicit memories for the particular events or experiences of one's life are __________ memories.


A) semantic
B) procedural
C) episodic
D) remote
E) implicit

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According to one hypothesis,each time a memory is retrieved from long-term storage it is temporarily susceptible to alteration-it may be either strengthened or weakened during this period.This process has been termed __________ .

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Cerebral ischemia is


A) a condition characterized by cancerous brain tumors.
B) a type of cerebral hemorrhage.
C) a shortage of blood to the brain.
D) an area of brain damage.
E) an area of brain damage caused by a toxin.

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When rats are NOT sure where they are,their place cells fire in accordance with where they


A) "think" they are.
B) "want" to be.
C) came from.
D) are going.
E) "expect" to be picked up.

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The specificity of LTP to particular synapses on the postsynaptic neuron is likely attributable to compartmentalizing effects of


A) serotonergic receptors.
B) glutamate.
C) dendritic spines.
D) axoaxonal synapses.
E) presynaptic inhibition.

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