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There are three genes located in the gene order A-B-C on a chromosome.Would you expect the recombination frequency to be higher between A and B or A and C?

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higher fro...

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Syntenic genes can assort independently when


A) they are very close together on a chromosome.
B) they are located on different chromosomes.
C) crossing over occurs rarely between the genes.
D) they are far apart on a chromosome and crossing over occurs frequently between the genes.
E) they are far apart on a chromosome and crossing over occurs very rarely between the genes.

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The products of meiosis yield the following results: PD = 1200 TT = 750 NPD = 50 What is the recombination frequency?

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RF = [(NPD + 1/2TT)/...

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What is the relationship between linked genes and syntenic genes? Are syntenic genes always linked,or are linked genes always syntenic? Describe what is meant by each term.

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Linked genes are always inherited togeth...

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What unit of physical distance between genes on a chromosome provides a convenient way to link the recombination frequencies for linked genes with their positions and order along a chromosome?

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map unit (...

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What type of test would you use to determine the relative order of more than two genes?

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three-poin...

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How is Newton Morton's statistical method helpful for calculating the overall probability of genetic linkage when allelic phase is unknown?

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Morton's method determines whether genet...

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Ascospores in yeast are not arranged in a particular order.Thus,the four haploid ascospores contained within a yeast ascus are known as what?

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In a two-point test-cross analysis,what are the "two points" being tested?

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The specific array of alleles making up a set of linked genes on a single chromosome is called a ________.

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haplotype

Recombination analysis allows for the mapping of genes because the frequency of crossing over is proportional to what?

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distance b...

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Describe why allelic phase is a major obstacle in mapping human genes.

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Allelic phase is the arrangement of diff...

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What is the highest possible frequency of recombination between linked genes that can be generated by any type of crossover event?

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Genetic linkage leads to the production of a significantly greater than expected number of gametes containing chromosomes with


A) allele combinations that are different from parental combinations.
B) parental combinations of alleles.
C) mutant alleles.
D) dominant alleles.
E) recessive alleles.

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If you are given a recombination frequency of 34% between genes X and Y and 27% between X and Z,can you predict the order of the three genes?


A) Yes;the order is X-Z-Y.
B) Yes;the order is X-Y-Z.
C) Yes;the order is Z-X-Y.
D) No;based on this data alone,the order could be Z-Y-X or X-Y-Z.
E) No;based on this data alone,the order could be X-Z-Y or Z-X-Y.

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Morgan realized that Bateson and Punnett had detected genetic linkage but couldn't explain their results because they performed the wrong cross.What type of cross did Morgan use for the analysis of genetic linkage of autosomal genes in Drosophila?

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two-point ...

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What would a Lod score of 3.2 tell you about genetic linkage? What information does the Θ value tell you?

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Scores of greater than 3.0 pro...

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For a given haplotype,the frequencies of alleles for gene Y are Y = 0.65 and Y' = 0.35,and the frequencies at gene Z are Z = 0.25 and Z' = 0.75.What is the predicted frequency of the Y'Z' haplotype?


A) 0.16
B) 0.26
C) 0.74
D) 0.84
E) 1.1

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B

Refer to this map to answer the following questions: Refer to this map to answer the following questions:     a) What is the distance between gene E and gene F? b) Assuming I = 0,what is the probability of no crossovers between gene D and gene E? c) Assuming I = 0,what is the probability of no crossovers between gene E and gene F? d) Considering both gene pairs,what is the proportion of nonrecombinant gametes? e) What is the predicted frequency of each parental gamete (DEF/def)? f) What is the recombination frequency between gene D and gene E? g) What is the recombination frequency between gene E and gene F? h) What is the frequency of two single recombinant gametes between genes D and E? i) What is the frequency of two single recombinant gametes between genes E and F? j) What is the frequency of each of the double-recombinant gametes,DeF and dEf? k) Fill in the blanks below to prove that the sum of the frequencies of the eight predicted gamete genotypes is equal to 1.0: _______ + _______ + _______ + _______ + _______ + _______ + _______ + _______ = 1 DEF def Def dEF DEf deF DeF dEf a) What is the distance between gene E and gene F? b) Assuming I = 0,what is the probability of no crossovers between gene D and gene E? c) Assuming I = 0,what is the probability of no crossovers between gene E and gene F? d) Considering both gene pairs,what is the proportion of nonrecombinant gametes? e) What is the predicted frequency of each parental gamete (DEF/def)? f) What is the recombination frequency between gene D and gene E? g) What is the recombination frequency between gene E and gene F? h) What is the frequency of two single recombinant gametes between genes D and E? i) What is the frequency of two single recombinant gametes between genes E and F? j) What is the frequency of each of the double-recombinant gametes,DeF and dEf? k) Fill in the blanks below to prove that the sum of the frequencies of the eight predicted gamete genotypes is equal to 1.0: _______ + _______ + _______ + _______ + _______ + _______ + _______ + _______ = 1 DEF def Def dEF DEf deF DeF dEf

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a) 12 cM b) 92% c) 88% d) (0.92)(0.88)= 0.8096 e) (0.5)(0.8096)= 0.4048 f) 8% g) 12% h) (0.08)(0.88)(0.5)= 0.0352 i) (0.12)(0.92)(0.5)= 0.0552 j) (0.08)(0.12)(0.5)= 0.0048 k) 0.4048 + 0.048 + 0.0352 + 0.0352 + 0.0552 + 0.0552 + 0.0048 + 0.0048 = 1

In a two-point test-cross analysis,a dihybrid F₁ fly is crossed to a


A) pure-breeding mate with a dominant phenotype (AABB) .
B) pure-breeding mate with a recessive phenotype (aabb) .
C) heterozygote mate (AaBb) .
D) mate that is dominant for one gene and recessive for the other (AAbb or aaBB) .
E) second dihybrid F₁ fly (sibling cross) .

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