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Which of the following statements about type IV reactions is FALSE?


A) Reactions are primarily due to T cell proliferation.
B) Reactions are not apparent for a day or more.
C) Cytokines initiate tissue damage.
D) Allergic contact dermatitis is an example.
E) Hemolytic disease of the newborn is an example.

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Graft-versus-host disease will most likely be a complication of a(n)


A) skin graft.
B) bone marrow transplant.
C) blood transfusion.
D) Rh incompatibility between mother and fetus.
E) corneal transplant.

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All hypersensitivities involve antibody-antigen reactions.

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An inherited immunodeficiency is termed ________ and a secondary immunodeficiency is also known as ________.


A) congenital;acquired
B) birth defect;inherited
C) dysgenesis;congenital
D) aplasia;SCID
E) immune syndrome;lymphoma

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When testing donated blood for compatibility you would find a person with O type blood


A) has O type antigens on their red blood cells.
B) will lack plasma antibodies to A and B type antigens.
C) will lack A and B red blood cell antigens.
D) lacks HLA and MHC antigens.
E) will have anti-O antibodies in their plasma.

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Vaccines against HIV have proven to be very effective in halting the spread of disease.

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A health care worker had a needlestick injury while drawing blood from an AIDS patient.Lab tests on the worker's serum were negative.Explain why the worker can still be infected even though her lab tests were negative.How should her health care be monitored?

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The worker can still be infected with HI...

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All of the following lead to drug-induced thrombocytopenic purpura.Which occurs first?


A) Antibodies and complement react with platelets.
B) Antibodies against haptens are formed.
C) Drug binds to platelets.
D) Platelets are destroyed.
E) Purpura occurs on the skin.

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The reasons for investigating stem cells to replace damaged organs and tissues in a patient include all of the following EXCEPT


A) the patient will not reject tissues produced with their stem cells.
B) adult stem cells can be successfully induced to develop into some specifically needed cell types.
C) embryonic stem cells can be coaxed into developing into any cell type in the body.
D) umbilical cord blood cells are less likely to cause GVHD than adult stem cell grafts.
E) pluripotent stem cells naturally occur even late in life in mammals.

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Table 19.1  Donor  Recipient  1. ABBRhAB,Rh+ 2. A,Rh+A,Rh 3. A+Rh+O,Rh+ 4. B,RhB,Rh+ 5. B,Rh+A,Rh+\begin{array} { | l | l | } \hline \text { Donor } & \text { Recipient } \\\hline \text { 1. } \mathrm { AB } ^ { \mathrm { B } } \mathrm { Rh } ^ { - } & \mathrm { AB } , \mathrm { Rh } ^ { + } \\\hline \text { 2. } \mathrm { A } , \mathrm { Rh } ^ { + } & \mathrm { A } , \mathrm { Rh } ^ { - } \\\hline \text { 3. } \mathrm { A } ^ { + } \mathrm { Rh } ^ { + } & \mathrm { O } , \mathrm { Rh } ^ { + } \\\hline \text { 4. } \mathrm { B } , \mathrm { Rh } ^ { - } & \mathrm { B } , \mathrm { Rh } ^ { + } \\\hline \text { 5. } \mathrm { B } , \mathrm { Rh } ^ { + } & \mathrm { A } , \mathrm { Rh } ^ { + } \\\hline\end{array} Which blood transfusions in Table 19.1 are incompatible?


A) 2 and 5
B) 1,2,and 3
C) 2,3,and 5
D) 3 and 4
E) 1 and 2

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Which of the following describes a cytotoxic autoimmune reaction?


A) Antibodies react to cell-surface antigens.
B) Antibodies are not made.
C) Cells are killed.
D) Immune complexes form.
E) Mediated by T cells.

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Which of the terms regarding treatments after transplantation of an organ is mismatched?


A) cyclosporine-suppression of B cells.
B) cyclosporine- kidney toxicity.
C) sirolimus-inhibit cell mediated and humoral immunity.
D) basiliximab-chimeric monoclonal.
E) tacrolimus-suppression of IL-2 secretion.

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Which of the following statements is true of phase 3 HIV infection?


A) HIV in blood stabilizes at 1000-10,000 per ml of blood.
B) CD4⁺ cell population drops to less than 200 cells per μl of blood.
C) HIV peaks to 10 million per ml of blood.
D) asymptomatic infection.
E) Seroconversion occurs.

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Xenotransplantation is an effective alternative to using isografts.

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Symptoms of delayed cell-mediated reactions are due to


A) IgE antibodies.
B) neutrophils.
C) cytokines.
D) IgG antibodies.
E) antigens.

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Skin tests are reliable indicators for the diagnosis of food-related allergies.

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Figure 19.1 Figure 19.1    -In immune complex reaction shown in Figure 19.1,what is the end result of the reaction? A) IgG is directed against cell membrane antigens. B) Complement is activated. C) Neutrophils are attracted and release enzymes. D) Endothelial cells are damaged. E) Antibodies destroy neutrophils. -In immune complex reaction shown in Figure 19.1,what is the end result of the reaction?


A) IgG is directed against cell membrane antigens.
B) Complement is activated.
C) Neutrophils are attracted and release enzymes.
D) Endothelial cells are damaged.
E) Antibodies destroy neutrophils.

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All of the following are true of hypersensitivity EXCEPT


A) it occurs in the presence of an antigen.
B) it is synonymous with "allergy."
C) it occurs when an individual is exposed to an allergen for the first time.
D) it is due to an altered immune response.
E) it requires previous exposure to an antigen.

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Differentiate type II from type III hypersensitivity reactions.

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Type II and Type III hypersensitivity re...

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Hemolytic disease of the newborn can result from an


A) Rh⁺ mother with an Rh⁻ fetus.
B) Rh⁻ mother with an Rh⁺ fetus.
C) AB mother with a B fetus.
D) AB mother with an O fetus.
E) Rh⁻ mother and an A fetus.

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