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Why might a researcher wish to design a drug that inhibited autoreceptors for a particular neurotransmitter?


A) To decrease release of the neurotransmitter from the axon terminal
B) To increase release of the neurotransmitter from the axon terminal
C) To automatically activate postsynaptic receptors
D) To reduce synthesis of the neurotransmitter

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An excitatory postsynaptic potential hyperpolarizes a local potential.

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Channels that open or close depending on local potential changes are called:


A) voltage-gated ion channels.
B) depolarization channels.
C) sodium-potassium pumps.
D) ligand-gated ion channels.

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Why does an action potential only reach a particular value?


A) Potassium channels close
B) Sodium channels close
C) Excitatory postsynaptic potentials cease
D) Sodium-potassium pump activity resumes

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Large molecule neurotransmitters are typical transported into vesicles in the:


A) axon terminal.
B) soma.
C) postsynaptic terminal.
D) axon hillock.

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All of the following is true for glutamate except:


A) Ionotropic receptors allow positively charged ions into the neuron.
B) All of the receptors for glutamate produce excitatory effects.
C) Glutamate is released from pyramidal neurons.
D) Glutamate is the most prominent excitatory neurotransmitter.

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The number of action potentials occurring per unit of time is referred to as the:


A) sodium-potassium pumping rate
B) propagation of action potentials.
C) firing rate.
D) action potential magnitude.

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Which of the following is an example of a concentration gradient?


A) Ions flowing through a barrier with selective permeability.
B) Ions flowing from to an area with an opposite electrical charge.
C) Ions flowing from an area of high concentration to low concentration.
D) Ions increasing in concentration in a graded manner.

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Calcium causes _____________,the fusing of synaptic vesicles to the axon membrane and release of stored neurotransmitters into the synaptic cleft

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Neurotransmitters may also bind to receptors outside of the synapse,a process called _____________ neurotransmission

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Where does the synthesis of large neurotransmitter molecules typically occur?


A) Postsynaptic terminal
B) Axon terminal
C) Soma
D) Vesicle

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List and describe the steps occurring in neurotransmission

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1.Synthesis of neurotransmitters 2.Actio...

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Depolarization means that the charge inside a cell approaches the charge outside of the cell.

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Compare and contrast ionotropic and metabotropic receptors.

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Physical proximity to parts of neuron wh...

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The activation of a neurotransmitter receptor is another way of stating that:


A) a neurotransmitter is bound to a receptor.
B) a conformational change occurred to the receptor.
C) an excitatory postsynaptic potential occurred.
D) exocytosis occurred.

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Why do action potentials only travel down the axon and not the other direction?


A) An area where an action potential just occurred is still in a refractory period.
B) Resting potentials change with direction of the nerve impulse.
C) Sodium-potassium pumps only act in one direction.
D) Actions potential do not cause depolarization.

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A(n) _______________ is an enzyme that causes phosphorylation of a substrate protein.


A) G-protein
B) substrate protein
C) protein kinase
D) effector enzyme

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GABA is thought of as an inhibitory neurotransmitter because:


A) GABA counteracts the excitatory effects of glutamate.
B) GABA's chemical structure inhibits cell function.
C) GABA receptors cause inhibitory effects.
D) GABA's receptors are metabotropic.

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What effect on a neuron's resting potential would a drug that stop sodium-potassium pump activity likely have?


A) The neuron's resting potential would be unaffected.
B) The neuron's resting potential would become hyperpolarized due to decreasing in potassium ions.
C) The neuron's resting potential would become depolarized due to a increase in sodium ions.
D) The neuron would not be able to produce an action potential.

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The binding of a neurotransmitter causes a _____________ change in the receptor to occur.

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