Question 1

The formation of a D-loop is associated with which of the following models of recombination?

Accepted Answer

A)  Double-stranded break model
B)  Holliday model
C)  Single-stranded break model

Question 2

Long-terminal repeats are unique to which group of transposons?

Accepted Answer

A)  Composite transposon
B)  Non-viral retro element
C)  Viral-like retro element
D)  Replicative transposon
E)  Insertion sequence

Question 3

Which enzyme is unique to the retro elements?

Accepted Answer

A)  Reverse transcriptase
B)  Reverse resolvase
C)  Transposase
D)  Integrase
E)  Reverse integrase

Question 4

Site-specific recombination occurs between homologous sequences of DNA.

Accepted Answer

A) True 
 B)False

Question 5

Which of the following may account for the process of gene conversion?

Accepted Answer

A)  DNA mismatch repair
B)  DNA gap repair
C)  Photolyase activity
D)  Nucleotide excision repair

Question 6

The integrase enzyme is responsible for inserting bacteriophage $\lambda$ into the host genome.

Accepted Answer

A) True 
 B)False  True

Question 7

In eukaryotic organisms, a single-stranded break in the DNA is required before recombination can begin during meiosis.

Accepted Answer

A) True 
 B)False  False

Question 8

Transposons that utilize an RNA intermediate for transposition are called _____.

Accepted Answer

A)  IS elements
B)  Retroviruses
C)  Retrotransposons
D)  Non-transposable elements C

Question 9

To date, there are not any indications that transposable elements offer a selective advantage to a species.

Accepted Answer

A) True 
 B)False

Question 10

Which of the following best describes the function of the RecA protein in

Accepted Answer

A)  Promotes strand invasion and formation of the D loop
B)  Recognizes double-stranded breaks in the DNA
C)  Is involved in the initial formation of the Holliday junctions
D)  Resolves Holliday junctions into separate chromosomes
E)  coli recombination?

Question 11

A heteroduplex is a DNA double helix that contains mismatches.

Accepted Answer

A) True 
 B)False

Question 12

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Accepted Answer

A)  A nick in only one strand of the DNA
B)  Double-stranded breaks in DNA
C)  DNA gap repair synthesis
D)  Heteroduplex formation

Question 13

Which of the following enzymes is required for a transposon to move?

Accepted Answer

A)  Integrase
B)  Jumpase
C)  Splicase
D)  Transposase

Question 14

Transposable elements in bacteria are commonly called insertion sequences.

Accepted Answer

A) True 
 B)False

Question 15

The human genome contains a unique gene for each immunoglobulin produced.

Accepted Answer

A) True 
 B)False

Question 16

What is the selfish DNA theory?

Accepted Answer

A)  A theory that explains how DNA point mutations are repaired within the genome.
B)  A theory that explains how transposable elements are repaired within the genome.
C)  A theory that attempts to explain the proliferation of transposable elements in a genome by comparing it to the action of a parasite.
D)  A theory that attempts to explain how the proliferation of transposons improves the evolutionary advantage of the host organism.

Question 17

Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?

Accepted Answer

A)  Ds
B)  C
C)  Sh
D)  Wx
E)  All of the answers are correct

Question 18

A bacteriophage that has integrated into the bacterial chromosome is called a prophage.

Accepted Answer

A) True 
 B)False

Question 19

The process of recombination occurs during metaphase I of meiosis.

Accepted Answer

A) True 
 B)False

Question 20

Recombination between sister chromatids produces new combinations of alleles that may be beneficial to the species.

Accepted Answer

A) True 
 B)False

Exam 19: Recombination and Transposition at the Molecular Level

The formation of a D-loop is associated with which of the following models of recombination?

Correct AnswerverifiedShow Answer

Long-terminal repeats are unique to which group of transposons?

Correct AnswerverifiedShow Answer

Which enzyme is unique to the retro elements?

Correct AnswerverifiedShow Answer

Site-specific recombination occurs between homologous sequences of DNA.

Correct AnswerverifiedShow Answer

Which of the following may account for the process of gene conversion?

Correct AnswerverifiedShow Answer

The integrase enzyme is responsible for inserting bacteriophage λ\lambdaλ into the host genome.

Correct AnswerverifiedTrue

In eukaryotic organisms, a single-stranded break in the DNA is required before recombination can begin during meiosis.

Correct AnswerverifiedFalse

Transposons that utilize an RNA intermediate for transposition are called _____.

Correct AnswerverifiedC

To date, there are not any indications that transposable elements offer a selective advantage to a species.

Correct AnswerverifiedShow Answer

Which of the following best describes the function of the RecA protein in

Correct AnswerverifiedShow Answer

A heteroduplex is a DNA double helix that contains mismatches.

Correct AnswerverifiedShow Answer

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Correct AnswerverifiedShow Answer

Which of the following enzymes is required for a transposon to move?

Correct AnswerverifiedShow Answer

Transposable elements in bacteria are commonly called insertion sequences.

Correct AnswerverifiedShow Answer

The human genome contains a unique gene for each immunoglobulin produced.

Correct AnswerverifiedShow Answer

What is the selfish DNA theory?

Correct AnswerverifiedShow Answer

Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?

Correct AnswerverifiedShow Answer

A bacteriophage that has integrated into the bacterial chromosome is called a prophage.

Correct AnswerverifiedShow Answer

The process of recombination occurs during metaphase I of meiosis.

Correct AnswerverifiedShow Answer

Recombination between sister chromatids produces new combinations of alleles that may be beneficial to the species.

Correct AnswerverifiedShow Answer

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The integrase enzyme is responsible for inserting bacteriophage $\lambda$ into the host genome.

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True

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False

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C

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