Question 1

All of the following pertain to fluoroquinolones,except

Accepted Answer

A)   they are broad spectrum.
B)   they include ciprofloxacin and levofloxacin.
C)   they are nephrotoxic.
D)   they are used to treat respiratory, urinary, and sexually transmitted infections.
E)   they are readily absorbed from intestines.

Question 2

Broad-spectrum drugs that disrupt the body's normal biota often cause ______.

Accepted Answer

A)   nephrotoxicity
B)   superinfections
C)   allergic reactions
D)   drug toxicity

Question 3

Aminoglycosides

Accepted Answer

A)   destroy peptidoglycan.
B)   are metabolic analogs of PABA and block folic acid synthesis.
C)   attach to the 30S ribosomal subunit and disrupt protein synthesis.
D)   damage cell membranes.
E)   block peptidases that cross-link glycan molecules.

Question 4

Drug susceptibility testing determines

Accepted Answer

A)   the patient's response to various antimicrobials.
B)   the pathogen's response to various antimicrobials.
C)   if normal biota will be affected by antimicrobials.
D)   if the drug is increasing to toxic levels in a patient.

Question 5

An ideal antimicrobial therapeutic drug exhibits all of the following characteristics,except

Accepted Answer

A)   they are nontoxic to host.
B)   they are easily broken down by host.
C)   they are easily administered.
D)   they have limited capacity to elicit resistance.
E)   they are nonallergenic.

Question 6

Bacteria can have a natural resistance to a drug to which they have never been exposed.

Accepted Answer

A) True 
 B)False

Question 7

Each of the following affect cell walls,except ______.

Accepted Answer

A)   penicillin
B)   cycloserine
C)   vancomycin
D)   erythromycin
E)   cephalosporin

Question 8

Each of the following contributes to emerging drug resistance except

Accepted Answer

A)   overuse of antibiotics.
B)   improper use of antibiotics.
C)   multiple drug therapy.
D)   ingestion of antibiotics with animal feed.
E)   addition of antibiotics to common household products.

Question 9

Which antibiotic is used to treat MRSA and VRE infections?

Accepted Answer

A)   Synercid
B)   Clindamycin
C)   Linezolid
D)   Azithromycin
E)   Clarithromycin

Question 10

Antibiotics that disrupt bacterial ribosomes can also affect

Accepted Answer

A)   eukaryotic large ribosomal subunit.
B)   eukaryotic small ribosomal subunit.
C)   ribosomal RNA.
D)   eukaryotic mitochondrial ribosomes.

Question 11

The first modern antimicrobial drugs were sulfa drugs.

Accepted Answer

A) True 
 B)False

Question 12

The drug that is used to treat typhoid fever and brain abscesses,but can cause aplastic anemia,is ______.

Accepted Answer

A)   chloramphenicol
B)   clindamycin
C)   ciprofloxacin
D)   bacitracin
E)   gentamicin

Question 13

The use of antibiotics in cattle feed leads to the development of antibiotic-resistant bacteria.

Accepted Answer

A) True 
 B)False

Question 14

Over 50 percent of all sales of medically important antibiotics in the United States are for livestock use.Why is this problematic for humans?

Accepted Answer

A)   The livestock will become resistant to the antibiotics and not respond to treatment when they have infections.
B)   Resistant bacteria grow in the animals and may then be passed to humans.
C)   The use of antibiotics for livestock means that there are not enough for use in the human population.
D)   The animals may become sick from the antibiotic ingestion.

Question 15

Why do researchers often include DNase in their antibiotic preparations to eliminate biofilms?

Accepted Answer

A)   Targeting the bacterial chromosome is the most effective way to kill biofilm bacteria.
B)   If the microbe's genome can be destroyed, the cell will die.
C)   The antibiotics cannot readily penetrate the extracellular debris, which often includes DNA from lysed cells.
D)   The antibiotics target the cell wall and the DNase targets the genome, effectively destroying the biofilm.

Question 16

Antimicrobial drugs that inhibit folic acid synthesis work with no side effects because mammals must get folic acid from their diet.

Accepted Answer

A) True 
 B)False

Question 17

Mebendazole,thiabendazole,and ivermectin are drugs used to treat _____ infections.

Accepted Answer

A)   bacterial
B)   fungal
C)   protozoan
D)   helminthic
E)   viral

Question 18

Which of the following is not a mode of action of antiviral drugs?

Accepted Answer

A)   Block penetration
B)   Block transcription and translation
C)   Inhibit DNA synthesis
D)   Block maturation
E)   Bond to ergosterol in the cell membrane

Question 19

Each of the following is a mechanism for drug resistance transfer between microorganisms,except ______.

Accepted Answer

A)   transposons
B)   R-plasmids
C)   conjugation
D)   mutation

Question 20

Drug toxicity occurs when an antimicrobial drug acts as antigen and stimulates an allergic response.

Accepted Answer

A) True 
 B)False

Exam 12: Antimicrobial Treatment

The first modern antimicrobial drugs were sulfa drugs.

Correct AnswerverifiedShow Answer

Bacteria can have a natural resistance to a drug to which they have never been exposed.

Correct AnswerverifiedShow Answer

Each of the following is a mechanism for drug resistance transfer between microorganisms,except ______.

Correct AnswerverifiedShow Answer

Each of the following contributes to emerging drug resistance except

Correct AnswerverifiedShow Answer

Drug susceptibility testing determines

Correct AnswerverifiedShow Answer

Mebendazole,thiabendazole,and ivermectin are drugs used to treat _____ infections.

Correct AnswerverifiedShow Answer

All of the following pertain to fluoroquinolones,except

Correct AnswerverifiedShow Answer

Each of the following affect cell walls,except ______.

Correct AnswerverifiedShow Answer

Why do researchers often include DNase in their antibiotic preparations to eliminate biofilms?

Correct AnswerverifiedShow Answer

Antibiotics that disrupt bacterial ribosomes can also affect

Correct AnswerverifiedShow Answer

Which antibiotic is used to treat MRSA and VRE infections?

Correct AnswerverifiedShow Answer

Over 50 percent of all sales of medically important antibiotics in the United States are for livestock use.Why is this problematic for humans?

Correct AnswerverifiedShow Answer

Antimicrobial drugs that inhibit folic acid synthesis work with no side effects because mammals must get folic acid from their diet.

Correct AnswerverifiedShow Answer

Aminoglycosides

Correct AnswerverifiedShow Answer

Broad-spectrum drugs that disrupt the body's normal biota often cause ______.

Correct AnswerverifiedShow Answer

Which of the following is not a mode of action of antiviral drugs?

Correct AnswerverifiedShow Answer

The drug that is used to treat typhoid fever and brain abscesses,but can cause aplastic anemia,is ______.

Correct AnswerverifiedShow Answer

An ideal antimicrobial therapeutic drug exhibits all of the following characteristics,except

Correct AnswerverifiedShow Answer

The use of antibiotics in cattle feed leads to the development of antibiotic-resistant bacteria.

Correct AnswerverifiedShow Answer

Drug toxicity occurs when an antimicrobial drug acts as antigen and stimulates an allergic response.

Correct AnswerverifiedShow Answer

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