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Visible,clear,well-defined patches in a monolayer of virus-infected cells in a culture are called ______.


A) patches
B) buds
C) plaques
D) cytopathic effects
E) pocks

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Who developed a rabies vaccine after realizing the disease was caused by something smaller than a bacterium?


A) Leeuwenhoek
B) Koch
C) Pasteur
D) Cohn
E) Ivanovski

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C

Which of the following is incorrect about prophages?


A) Present when the virus is in lysogeny
B) Formed when viral DNA enters the bacterial chromosome
C) Replicated with host DNA and passed on to progeny
D) Cause lysis of host cells
E) Occur when temperate phages enter host cells

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Creutzfeldt-Jacob disease is


A) caused by a chronic latent virus.
B) initiated by an oncogenic virus.
C) caused by a viroid.
D) a spongiform encephalopathy of humans.
E) also called "mad cow disease."

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D

In transduction,the viral genome


A) initiates lysis of the host.
B) includes DNA from the previous host.
C) is replicated in the cytoplasm.
D) is replicated in the nucleus.

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Viruses mutate,and some viruses have not been discovered.

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Which of the following occurs during assembly?


A) The nucleocapsid is formed.
B) New viral nucleic acid is formed.
C) Viral spikes insert in host cell membrane.
D) The nucleocapsid is formed and viral spikes insert in host cell membrane.
E) The viral envelope and the host cell membrane fuse.

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The process of dissolving the envelope and capsid to release the viral nucleic acid is ______.


A) adsorption
B) penetration
C) uncoating
D) synthesis
E) assembly

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Bacteriophages do not undergo adsorption to specific host cell receptors prior to penetration.

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Viruses are unable to multiply outside of a host cell.

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Sterilizing filters have a pore size of 0.22 μ\mu m.Which of the following statements is true?


A) Bacterial cells are typically between 1,000-10,000 nm and pass through the filter, whereas most viruses are between 20 and 200 nm and are therefore blocked.
B) Bacterial cells are typically between 1-10 μ\mu m and pass through the filter, whereas most viruses are between 20 and 200 nm and are therefore blocked.
C) Bacterial cells are typically between 1-10 μ\mu m and are blocked by the filter, whereas most viruses are between 20 and 200 nm and therefore pass through.
D) Bacterial cells are typically between 1-10 nm and are blocked by the filter, whereas most viruses are between 20 and 200 μ\mu m and therefore pass through.

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T-even phages ______.


A) include the poxviruses
B) infect Escherichia coli cells
C) enter host cells by engulfment
D) have helical capsids

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B

The correct sequence of events in viral multiplication is


A) penetration, uncoating, synthesis, adsorption, assembly, and release.
B) uncoating, penetration, synthesis, assembly, absorption, and release.
C) adsorption, penetration, uncoating, synthesis, assembly, and release.
D) assembly, synthesis, uncoating, release, penetration, and adsorption.
E) adsorption, release, synthesis, uncoating, assembly, and penetration.

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Diagnosis of viral infections sometimes involves analyzing the patient's blood for specific _____ that the immune system produces against the virus.


A) glycoproteins
B) antibodies
C) complement proteins
D) antigens

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The envelope of enveloped viruses


A) is identical to the host plasma membrane.
B) is only composed of host endomembrane.
C) does not contain spikes.
D) is obtained by viral budding or exocytosis.
E) makes the virus very susceptible to drug therapy.

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Which of the following is not a typical capsid shape?


A) Tetrahedral
B) Complex
C) Helical
D) Icosahedron

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Which of the following will not support viral cultivation?


A) Live lab animals
B) Embryonated bird eggs
C) Primary cell cultures
D) Continuous cell cultures
E) All of the choices will support viral cultivation.

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What type of phage enters an inactive prophage stage?


A) Primary
B) Secondary
C) Temperate
D) Temporary
E) Transformed

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Satellite viruses are


A) also called viroids.
B) dependent on other viruses for replication.
C) the cause of spongiform encephalopathies.
D) significant pathogens of plants.

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Compared to bacteria that have a typical size range between 1-10 μ\mu m,


A) viruses range in size between 20-200 nm and are much larger than bacterial cells.
B) viruses have a much greater size range; between 22 nm and 1000 nm.
C) all viruses are 22 nm.
D) viruses are larger and are blocked by sterilizing filters.

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