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Aminoacyl-tRNA synthetase is the enzyme that


A) folds tRNA molecules into their proper configuration.
B) causes tRNA molecules to bind to the aminoacyl site of a ribosome.
C) produces tRNA by "reading" DNA molecules.
D) adds the appropriate amino acid to an uncharged tRNA.

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D

Ribosomes are composed of


A) tRNA and protein.
B) mRNA and protein.
C) rRNA and protein.
D) only proteins folded together.

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A tRNA molecule looks like a compact ____ when it is folded into its functional configuration.


A) G
B) L
C) C
D) P

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A neomorphic mutation results in an allele that


A) produces no gene product.
B) produces a nonfunctional gene product.
C) produces novel proteins or cause inappropriate expression resulting in a new phenotype.
D) produces proteins that aggregate with wild-type subunits, inactivating them.
E) produces an altered protein that results in a wild-type phenotype. Blooms Level 2: Understand

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In the usual flow of genetic information (often called the Central Dogma) , which of the following best represents the expression of genes?


A) Protein-RNA-DNA
B) DNA-RNA-Protein
C) RNA-DNA-Protein
D) DNA-Protein-RNA

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Which of the following is required for initiation of eukaryotic translation?


A) Shine-Dalgarno sequence
B) 5' cap
C) 3' poly(A) tail
D) N-formylmethionine
E) Introns
Blooms Level 1: Remember

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Drugs like AZT, ddC, or ddI work against the AIDS virus because they


A) destroy viral proteins.
B) prevent the formation of viral mRNA.
C) block the action of viral tRNA.
D) look like nitrogenous bases and block viral reverse transcriptase.

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The cellular organelle responsible for protein synthesis is the


A) nucleus.
B) mitochondria.
C) centrioles.
D) ribosome.

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Which of these terms is NOT used as a nickname for a stop codon?


A) emerald
B) amber
C) opal
D) ochre

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A codon is a three-base sequence of


A) mRNA that codes for an amino acid.
B) rRNA that codes for an amino acid.
C) tRNA that codes for an amino acid.
D) DNA that codes for an amino acid.

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A mutation that is characterized by a change in the DNA sequence, but no change in the resulting protein sequence, is called a


A) frameshift mutation.
B) missense mutation.
C) silent mutation.
D) nonsense mutation.

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In the modification of eukaryotic mRNA, a "cap" consisting of a/an _________ and a tail consisting of _______ are usually added to the transcript.


A) acetyl group, multiple cytosines
B) multiple guanines, methyl group
C) multiple thymines, acetyl group
D) methyl group, multiple adenines

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A typical example of a genetic system that employs RNA splicing is


A) the genes that code for the segments in an earthworm.
B) the genes responsible for making antibodies in humans.
C) the HIV virus genes.
D) the genes that enable RNA splicing.

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B

The retroviruses, including HIV, are unique because they do reverse


A) replication.
B) transcription.
C) splicing.
D) translation.

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RNA polymerase binds to a sequence called a/an ______________ before beginning transcription.


A) promoter
B) operator
C) structural gene
D) replication origin

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Nonsense codons are


A) codons that code for multiple amino acids.
B) codons that do not code for an amino acid.
C) codons that can be read forward or backward.
D) start codons.

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A mutation that changes a codon sequence, and subsequently changes the amino acid that should have been placed at that point in the polypeptide chain, is called a


A) frameshift mutation.
B) missense mutation.
C) silent mutation.
D) nonsense mutation.

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Experiments that are done inside a living cell are describe by the Latin term


A) in vino.
B) in vito.
C) in vivo.
D) in vitro.

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Experiments that are done outside a living cell are describe by the Latin term


A) in vino.
B) in vito.
C) in vivo.
D) in vitro.

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In the digestive system, some protease enzymes must be secreted as an inactive form and then activated later by proteolytic cleavage once outside of the secreting cell.This is to prevent active proteases from damaging the secreting cells.What is the category of precursor proteins of this type?


A) Ubiquitins
B) Zymogens
C) Glycosides
D) Activins

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B

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