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Inhibiting the actions of helper T lymphocytes may impair humoral immunity.

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Interferons


A) stimulate viral replication.
B) provide humoral immunity.
C) provide nonspecific immunity.
D) are produced by viruses.

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Mutation in the variable regions of the heavy and light chains would directly change the antigen binding site.

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Viral infection of target cells results in


A) the presentation of viral antigens in class-2 MHC molecules.
B) the activation of cytotoxic T cells when the CD4 coreceptor is occupied.
C) the presentation of viral antigens in class-1 MHC molecules.
D) activation of helper T cells when the CD8 coreceptor is occupieD.

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The two categories of immune defensive mechanisms are __________ and ___________.


A) innate (nonspecific) immunity,adaptive (specific) immunity.
B) passive immunity,active immunity.
C) heavy immunity,light immunity.
D) direct immunity,indirect immunity.

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T cells have receptors for antigens and will bind to free antigens like B cells.

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The success of vaccinations was first demonstrated by


A) Jenner.
B) Pasteur.
C) Landsteiner.
D) Kupffer.

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Helper T lymphocytes interact specifically with antigens presented with class-2 MHC molecules.

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Which cell combats most bacterial infections?


A) B lymphocyte
B) T lymphocyte

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What is the function of granzymes?


A) polymerize cell membranes to form a large pore
B) activate caspases that destroy the cell's DNA
C) bind to the plasma membrane of the host cell
D) activate complement

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Antibodies act as "red flags" to identify antigens or pathogenic organisms for phagocytosis or action by complement.

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How does the immune system recognize a foreign cell?


A) The presence of toll-like receptors.
B) The presence of organ-specific phagocytes.
C) The presence of pathogen-associated molecular patterns.
D) The presence of complement.

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Tissue transplants should have matching ______ to prevent rejection in the host.


A) MHC molecules
B) perforins
C) interleukins
D) All of the choices are correct.

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Mutations in polypeptides called _____________ that are produced by T cells would prevent T cells from destroying infected cells.


A) perforins
B) antibodies
C) histamines
D) interferons

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Phagocytotic leukocytes involved in the inflammatory response generally do not reenter system circulation.

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What molecule is used to produce lymphokine-activated killer cells to treat some types of cancer?


A) interleukin-2
B) interleukin-1
C) interleukin-4
D) G-CSF

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The binding of FAS and its FAS ligand will trigger


A) interferon release.
B) T lymphocyte activation.
C) antibody production.
D) T lymphocyte apoptosis.

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