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Exam 5: Beyond Mendels Laws

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Question 21

Multiple Choice

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When the cystic fibrosis gene was discovered in 1989,only one mutation was described,and a diagnostic test was developed to detect it.Over the years,as more mutations were discovered,they were added to the test panel.Today,most pregnant women are offered a CF test that detects 100 or so alleles,although more than 1600 mutations have been discovered.Which of these is reflected by the given facts?

A) The presence of multiple alleles
B) The presence of pleiotropy
C) The presence of phenocopy
D) The presence of lethal alleles

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Question 22

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A,B,and C are linked genes.Recombination between A and B is 3%;between A and C is 6%;and between B and C is 9%.What is the order of these genes on the chromosome?

A) A-B-C
B) A-C-B
C) B-C-A
D) B-A-C

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Question 23

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Two different alleles for the same mitochondrial gene is called

Mitochondrial disorders are probably very rare because

Several members of the Fitzsimmons family have polydactyly,and they differ in their numbers of extra fingers and toes.Yet,certain relatives who should have extra digits don't,such as Megan Fitzsimmons.She has two children,a son with two extra fingers and a daughter with an extra toe,and her father has an extra digit on each hand and foot.Polydactyly in this family is

In a heterozygote for two linked genes,both dominant alleles are on one chromosome and both recessive alleles are on another chromosome.The genes are said to be in

Genes that are situated close on a chromosome 2-14-2013

Epistasis and multiple alleles differ in that

Mitochondrial disorders tend to cause great fatigue because

Hairlessness in dogs is inherited from a single dominant allele.Inheriting two dominant alleles is lethal for an embryo.Ralph and Penelope are both hairless dogs.What is the probability that Penelope will give birth to a puppy with hair?

Clara has alkaptonuria.Her symptoms include back spasms,dark urine,arthritis,hearing loss,kidney stones,heart valve damage,and darkened ear tips.This condition is therefore

Some combinations of recessive alleles cause problems so severe that a may fetus cease to develop.Such lethal allele combinations appear to alter Mendelian ratios because

A and B are linked genes.A heterozygote for both genes would show which configuration if the genes are in cis?

The mitochondrial genome consists of _____ genes.

Marfan syndrome can be caused by mutations in either of two genes involved in the disorder,but mutations in one of the genes blocks activity of the other.This means that Marfan syndrome demonstrates

Familial hypercholesterolemia illustrates incomplete dominance in humans because

A and B are linked genes.In a study of 100 offspring,94 had parental genotypes for A and B,while 6 were recombinants.A and B are _____ map units apart.

A man who has normal hearing and has a recessive deafness allele on chromosome 17 marries a woman who also has normal hearing and also has a recessive deafness allele,but this allele is on chromosome 3.The probability that their children will be deaf due to either of these mutated genes is closest to

Geneticists construct linkage maps of chromosomes by

Morris is a big,healthy bull.One spring,he fathers ten calves,but five of them are stillborn,their muscles very rigid in a phenotype called "contracture." Farm animals often mate with their close relatives.So,three of the dams (mothers of the stillborns) are also Morris' daughters,and the fourth is his half-sister.The large number of stillborns is most likely due to