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Class I MHC genes code for


A) certain secreted complement components.
B) markers that display unique characteristics of self.
C) all HLA antigens.
D) receptors located primarily on macrophages and B cells.
E) all of the choices are correct.

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Cody is 4 months old and is given a DTaP injection by his pediatrician as part of the routine immunization schedule.What type of immunity will develop as a result of this?


A) Natural active immunity
B) Artificial passive immunity
C) Natural passive immunity
D) Artificial active immunity
E) None of the choices will protect him.

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The bone marrow is where


A) immune responses to antigen occur.
B) blood stem cells give rise to immature lymphocytes.
C) antigen is filtered from the blood.
D) antigen is filtered from tissue fluid.
E) T lymphocytes complete maturation.

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The process of clonal deletion is designed to


A) destroy clones of lymphocytes able to react to self molecules.
B) slow down the primary immune response to an antigen.
C) slow down the secondary immune response to an antigen.
D) limit the number of lymphocyte clones an individual has in order to make the system more efficient.
E) slow down the immune system in the elderly.

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Which kind of T cell synthesizes perforins and granzymes to destroy bacteria, viral infected cells, and cancer cells?


A) TC
B) TH
C) CD4
D) MHC

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Edward Jenner's work involved


A) inoculation of dried pus from smallpox pustules into a person to stimulate immunity.
B) development of passive immunotherapy.
C) development of an immunization to protect people against cowpox.
D) immunization using a related, less pathogenic organism to give protection against a more pathogenic one.
E) All of the choices are correct.

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Describe the major histocompatability complex with regard to its: a) location, b) composition, c) relationship to specific cell markers, and d) role in regulation of immune reactions.

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The major histocompatibility complex (MH...

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Class II MHC genes code for


A) certain secreted complement components.
B) self receptors recognized by natural killer cells.
C) all HLA antigens.
D) receptors located primarily on macrophages, dendritic cells, and B cells.
E) all of the choices are correct.

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Antigen presenting cells


A) include dendritic cells.
B) include macrophages.
C) engulf and modify antigen to be more immunogenic.
D) hold and present processed antigen on their cell membrane surface.
E) All of the choices are correct.

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All of the following are characteristics of IgM, except


A) it has 10 antigen binding sites.
B) it contains a central J chain.
C) it is the first class synthesized by a plasma cell.
D) it can fix complement.
E) it is a dimer.

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The monomer subunit of immunoglobulin molecules has all the following, except


A) two identical heavy polypeptide chains.
B) two identical light polypeptide chains.
C) disulfide bonds between polypeptide chains.
D) four antigen binding sites.
E) a variable and constant region on each polypeptide chain.

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An example of artificial passive immunity would be


A) chickenpox infection is followed by lifelong immunity.
B) chickenpox vaccine triggers extended immunity to chickenpox.
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta.
E) None of the choices are correct.

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Lymphocytes:


A) possess MHC antigens for recognizing self.
B) have membrane receptors that recognize foreign antigens.
C) gain tolerance to self by destruction of lymphocytes that could react against self.
D) develop into clones of B and T cells with extreme variations of specificity.
E) all of the choices are correct.

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The albumin fraction of serum separated by electrophoresis will contain most of the antibodies.

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The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is


A) IgA.
B) IgD.
C) IgE.
D) IgG
E) IgM.

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Herceptin is an example of a monoclonal antibody-based drug for


A) asthma.
B) Chron's disease.
C) breast cancer.
D) respiratory syncytial virus.
E) All of the choices are correct.

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Autoantigens are types of self-antigens that initiate an autoimmune response that can cause damage to host tissue.

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Which are the first to attack cancer cells and virus-infected cells?


A) helper T cells
B) suppressor T cells
C) cytotoxic T cells
D) delayed hypersensitivity T cells
E) natural killer (NK) cells

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An example of artificial active immunity would be


A) chickenpox infection is followed by lifelong immunity.
B) chickenpox vaccine triggers extended immunity to chickenpox.
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta.
E) None of the choices are correct.

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Which cells' direct involvement are required for cell-mediated immunity?


A) T-cells
B) B-cells
C) Bacterial cells
D) Viral components
E) Neutrophils

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