Question 1

Cholesterol is a precursor to
(I) prostaglandins
(II) vitamin K
(III) steroid hormones such as androgens
(IV) bile acids

Accepted Answer

A)  I,III,IV
B)  I,II,III,IV
C)  III only
D)  IV only
E)  III,IV

Question 2

Which of the following is FALSE regarding HMG-CoA reductase?

Accepted Answer

A)  HMG-CoA reductase is highly regulated.
B)  The active site is tightly bound by statins.
C)  HMG-CoA reductase levels are increased as a result of high cholesterol concentrations in the ER
D)  HMG-CoA reductase levels are decreased as a result of high cholesterol concentrations in the ER.
E)  HMG-CoA reductase is levels are decreased by the same factor that down regulated production of the LDL receptors

Question 3

Which enzyme catalyses the key regulatory step of cholesterol synthesis?

Accepted Answer

A)  " β\betaβ -ketothiolase"
B)  "HMG-CoA synthase"
C)  "HMG-CoA reductase"
D)  "mevalonate-5-phosphotransferase"
E)  "phenyltransferase"

Question 4

Which of the following statements about peroxisomes is FALSE?

Accepted Answer

A)  " β\betaβ  oxidation in peroxisomes can shorten very long fatty acids."
B)  "Mammalian peroxisomes can synthesize some lipids,including bile salts."
C)  "In plants,peroxisomes and glyoxysomes serve as the site of  β\betaβ  oxidation."
D)  "Long chain fatty acids are transported into the peroxisome via a carnitine carrier protein where they are activated for oxidation."
E)  " β\betaβ  oxidation in peroxisomes varies slightly from the mitochondrial process."

Question 5

Matching
Choose the correct answer from the list.Not all the answers will be used.

-________ is formed from ordered sequence of condensation of isoprene units.

Accepted Answer

A)   HDL
B)   propionyl-CoA
C)   LDL
D)   Dihydroxyacetone phosphate
E)   malonyl-CoAF)  ACPG)  chylomicronsH)  phosphopantetheineI)  flavinJ)  albuminK)  ketone bodiesL)  cholesterol

Question 6

Which of the following components would be condensed to form acetoacetate?

Accepted Answer

A)  acetyl CoA and acetyl-CoA
B)  HMG-CoA and acyl-CoA
C)  acetone and betahydroxybutyrate
D)  malonyl-CoA and acyl-CoA
E)  DHAP and glycerol-3-phosphate

Question 7

LDL taken up by the liver is

Accepted Answer

A)  broken down into fatty acids and amino acids.
B)  taken up by the ER and used to control synthesis of HMG CoA reductase and LDL receptor synthesis.
C)  converted into clathrin and recycled.
D)  irreversibly bound to LDL receptors.
E)  excreted in a clathrin coated vesicle.

Question 8

Which statement concerning phospholipid synthesis is true?

Accepted Answer

A)  Addition of polar "head groups" to diacylglycerol usually involves CDP derivatives.
B)  Addition of polar "head groups" to diacylglycerol usually involves UDP adducts.
C)  Addition of fatty acyl "tails" to glycerol usually involves CDP adducts.
D)  Addition of fatty acyl "tails" to glycerol usually involves UDP adducts.
E)  None of the above is true.

Question 9

Which of the following statements about apolipoproteins (with the possible exception of apoB-100) is TRUE?
(I) The apolipoproteins are water-soluble and loosely associate with the lipoproteins.
(II) The apolipoproteins contain helices with hydrophobic and hydrophilic groups on opposite sides of the helical cylinder.
(III) The apolipoproteins are synthesized in the intestinal tissues.
(IV) The apolipoproteins appear to float on the surface of phospholipids.

Accepted Answer

A)  I only
B)  I and II
C)  III,IV
D)  I,II,III
E)  I,II,IV

Question 10

Which of the following diets would most likely promote the formation of ketone bodies?

Accepted Answer

A)  high simple carbohydrates,low fat
B)  high complex carbohydrates,high fructose
C)  high fat,high protein,low carbohydrate
D)  low fat,high protein,high complex carbohydrates
E)  high fructose;high whole grain carbohydrates

Question 11

Which of the following would result in a net increase in uptake of LDL by the liver?

Accepted Answer

A)  increased availability of LDL receptors
B)  high levels of cholesterol synthesis
C)  increased availability of clathrin triskelions
D)  all of the above
E)  none of the above

Exam 20: Lipid Metabolism

Correct Answer
verified

LDL taken up by the liver is

Correct Answer
verified

Which of the following diets would most likely promote the formation of ketone bodies?

Correct Answer
verified

Cholesterol is a precursor to (I) prostaglandins (II) vitamin K (III) steroid hormones such as androgens (IV) bile acids

Correct Answer
verified

Which enzyme catalyses the key regulatory step of cholesterol synthesis?

Correct Answer
verified

Which statement concerning phospholipid synthesis is true?

Correct Answer
verified

Which of the following components would be condensed to form acetoacetate?

Correct Answer
verified

Which of the following statements about peroxisomes is FALSE?

Correct Answer
verified

Which of the following is FALSE regarding HMG-CoA reductase?

Correct Answer
verified

Matching Choose the correct answer from the list.Not all the answers will be used. -________ is formed from ordered sequence of condensation of isoprene units.

Correct Answer
verified

Which of the following would result in a net increase in uptake of LDL by the liver?

Correct Answer
verified

Exam 20: Lipid Metabolism

Correct AnswerverifiedShow Answer

LDL taken up by the liver is

Correct AnswerverifiedShow Answer

Which of the following diets would most likely promote the formation of ketone bodies?

Correct AnswerverifiedShow Answer

Cholesterol is a precursor to (I) prostaglandins (II) vitamin K (III) steroid hormones such as androgens (IV) bile acids

Correct AnswerverifiedShow Answer

Which enzyme catalyses the key regulatory step of cholesterol synthesis?

Correct AnswerverifiedShow Answer

Which statement concerning phospholipid synthesis is true?

Correct AnswerverifiedShow Answer

Which of the following components would be condensed to form acetoacetate?

Correct AnswerverifiedShow Answer

Which of the following statements about peroxisomes is FALSE?

Correct AnswerverifiedShow Answer

Which of the following is FALSE regarding HMG-CoA reductase?

Correct AnswerverifiedShow Answer

Matching Choose the correct answer from the list.Not all the answers will be used. -________ is formed from ordered sequence of condensation of isoprene units.

Correct AnswerverifiedShow Answer

Which of the following would result in a net increase in uptake of LDL by the liver?

Correct AnswerverifiedShow Answer

Correct Answer
verified

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Correct Answer
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Correct Answer
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Correct Answer
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