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All of the following are examples of transcriptional regulation in prokaryotes exceptــــــــــــــــــــــ .


A) binding of a repressor to an operator
B) premature termination of RNA polymerase during transcription elongation
C) binding of cAMP-CRP complex to the lac operon of Escherichia coli
D) over-riding termination by anti-terminator proteins

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B

Global regulatorsــــــــــــــــــــــــــ .


A) control large numbers of genes in response to a broad,general signals
B) control large numbers of genes in response to a specific signal
C) control small numbers of genes in response to broad,general signals
D) control small numbers of genes in response to a specific signal

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Which of the following is an example of negative regulation?


A) A gene is switched on in the presence of an activator.
B) A gene is de-repressed.
C) A gene is induced.
D) A gene is switched off by a repressor protein.

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Autoregulation occurs when ــــــــــــــــــــ.


A) IPTG binds to LacI
B) allo-lactose binds to LacI
C) a repressor binds to its own gene to prevent transcription
D) CRP binds to cAMP and the the lac operon

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C

All of the following are associated with two-component regulatory systems exceptـــــــــــــــــــــــــ .


A) gratuitous inducer
B) phosphorelay
C) DNA binding regulator
D) sensor kinase

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Alternative sigma factors exist for all of the following exceptــــــــــــــــــــــ .


A) heat shock
B) nitrogen control
C) flagellar motion
D) exponential phase

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Some nucleotides are involved in transcriptional regulation.

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True

Transcriptional elements that bind to a DNA molecule where the gene they regulate is located areــــــــــــــ .


A) trans-acting elements
B) cis-acting elements
C) positive regulators
D) negative regulators

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Which of the following is not an inducer of the lac operon?


A) allo-lactose
B) IPTG
C) glucose
D) lactose

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Gratuitous inducers ــــــــــــــــــــــــ.


A) are metabolized like the natural inducer
B) are not broken down
C) are nutrient sources
D) are competitive inhibitors

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