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_____ combines genetics and light to control targeted cells in living tissue.


A) Photogenetics
B) Optogenetics
C) Infragenetics
D) None of the answers is correct.

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_____ is a neurological disorder that is linked to periods of excessive neural synchrony.


A) Epilepsy
B) Parkinson disease
C) Multiple sclerosis
D) Stroke

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The patch technique involves:


A) placing the tip of a microelectrode on an axon.
B) recording between two microelectrodes,one inside the axon and the other outside.
C) placing the tip of the microelectrode in an axon and applying some back suction.
D) placing the tips of two microelectrodes in an axon and recording between them.

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During an action potential:


A) the voltage of the cell membrane drops to zero and then returns to -70 mV.
B) the voltage of the cell membrane drops to zero,returns to about -100 mV,and then goes to 70 mV.
C) the voltage of the cell membrane goes to about +30 mV and then drops to -70 mV.
D) the voltage of the cell membrane goes to about +30 mV,drops to -100 mV,and then goes to -70 mV.

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_____ produce(s) myelin in the peripheral nervous system,whereas _____ produce(s) myelin in the central nervous system.


A) Ependymal cells;Schwann cells
B) Astroglia;oligodendroglia
C) Oligodendroglia;Schwann cells
D) Schwann cells,oligodendroglia

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The negative charge inside of the cell membrane is largely a product of the presence of negatively charged:


A) potassium ions.
B) sodium ions.
C) protein anions.
D) All of the answers are correct.

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Hair receptors are associated with:


A) taste.
B) vision.
C) hearing and balance.
D) touch.

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Saltatory conduction refers to:


A) sodium concentration in the extracellular fluid.
B) action potentials that are facilitated by sodium.
C) action potentials jumping from one node to the next.
D) the leakage of the sodium channels that require the existence of a sodium-potassium pump.

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Voltage-sensitive sodium channels are active:


A) whenever the cell membrane starts to depolarize.
B) when the voltage across the membrane reaches zero.
C) when the threshold voltage of the cell is reached.
D) when the voltage across the membrane reaches +30 mV.

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When Richard Caton first measured fluctuations on a voltmeter from electrodes placed on the scalp of a human subject,he was recording what we now call:


A) the electroencephalogram.
B) the action potential.
C) the magnetoencephalogram.
D) axonal conductance.

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The propagation of the nerve impulse is:


A) not decremental.
B) related to the opening of potassium and sodium ion channels.
C) similar to the effect of falling dominoes.
D) All of the answers are correct.

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Research on optogenetics and light-sensitive ion channels has revealed that channel rhodopsin-2 can be used to _____ neurons and halorhodopsin can be used to _____ neurons.


A) hyperpolarize;depolarize
B) depolarize;hyperpolarize
C) destroy;depolarize
D) depolarize;destroy

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The speed of information flow in a nerve was first measured by:


A) Hermann von Helmholtz.
B) Wilder Penfield.
C) Eduard Hitzig.
D) Gustave Fritsch.

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Inhibitory postsynaptic potentials (IPSPs) are associated with:


A) the opening of potassium channels,allowing the outflow of potassium.
B) the opening of sodium channels,allowing the influx of sodium.
C) the closing of potassium channels,stopping the influx of potassium.
D) the closing of sodium channels,stopping the influx of potassium.

Correct Answer

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The symptoms of multiple sclerosis are caused by:


A) excess myelin on axons.
B) loss of myelin around axons.
C) excess excitatory input.
D) excess inhibitory input.

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The action potential normally consists of the summed current changes caused by the _____ and the _____.


A) inflow of sodium;outflow of potassium
B) outflow of sodium;inflow of potassium
C) inflow of calcium;outflow of potassium
D) inflow of sodium;outflow of chloride

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_____ is the term used to denote reverse movement of the action potential into the dendrites.


A) EPSP reversal
B) Back propagation
C) Inverse IPSP
D) None of the answers is correct.

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For an EPSP to cause another action potential,the stimulation must reach the _____,which is (are) rich in voltage-sensitive ion channels.


A) initial segment (axon hillock)
B) cell body
C) dendrites
D) terminal buttons

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Sodium channels close when the membrane potential reaches approximately:


A) +50 mV.
B) +30 mV.
C) -50 mV.
D) 0 mV.

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EPSPs are associated with _____,whereas IPSPs are associated with _____.


A) opening of sodium channels;opening of potassium channels
B) opening of sodium channels;closing of potassium channels
C) closing of sodium channels;opening of potassium channels
D) opening of calcium channels;closing of potassium channels

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