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An effective treatment for REM sleep behavior disorder is the administration of


A) antidepressant drugs.
B) the drug clonazepam.
C) drugs that block serotonin receptors.
D) drugs that facilitate both serotonin and catecholamine activity.
E) drugs that block hypocretin 2 receptors.

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A key source of noradrenergic neurons in the brain is the


A) nucleus accumbens.
B) hippocampus.
C) raphe nuclei.
D) striatum.
E) locus coeruleus.

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Most of the serotonin neurons in the brain are located within the


A) nucleus accumbens.
B) reticular formation.
C) raphe nuclei.
D) striatum.
E) locus coeruleus.

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C

Prolonged sleep deprivation in humans results in


A) impaired ability to perform physical labor.
B) psychosis.
C) some perceptual distortions.
D) subsequent rebound recovery of lost slow-wave sleep.
E) a mild form of bipolar disorder.

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C

Persons suffering from fatal familial insomnia resemble sleep-deprived rats in terms of


A) weight gain.
B) weight loss.
C) relaxation
D) mood disorder.
E) night-time overeating.

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The increased arousal and sleeplessness produced by amphetamine is related to the release of


A) norepinephrine.
B) serotonin.
C) acetylcholine.
D) dopamine.
E) GABA.

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Which of the following is true of sleeping medications?


A) Sleeping pills can lead to daytime hangovers.
B) Sleeping pills directly alter the cause of insomnia.
C) Insomnia is a disease that can be treated by a pill.
D) Unlike other drugs, persistent use of sleeping pills does not lead to tolerance.
E) Sleeping pills are more effective when combined with alcohol.

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The various stages of sleep are easily distinguished by


A) visible changes in respiration.
B) changes in motor movements involving speech..
C) changes in the electrical activity of the brain.
D) changes in consciousness.
E) the quality and quantity of dreams.

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________ refers to the vivid dreams that may occur during sleep paralysis.


A) Apnea
B) Hypnagogic hallucination
C) Cataplexy
D) Night terror
E) Somnambulism

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Explain the process by which light acts on the suprachiasmatic nucleus (SCN) to control the circadian rhythm.

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Pulses of light induce FOS activity with...

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The metabolism of glycogen within astrocytes produces ________, which in turn promotes ________.


A) adenosine; wakefulness
B) GABA; REM sleep
C) adenosine; slow-wave sleep
D) a benzodiazepine ligand; slow-wave sleep
E) GABA; slow-wave sleep

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The disorder known as ________ shares common attributes (symptoms as well as treatments) with those of narcolepsy.


A) anxiety disorder
B) obsessive-compulsive disorder
C) mania
D) panic attack
E) depression

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A person who exhibits sudden paralysis but remains conscious may be suffering from an episode of ________.

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The observation that a person's brain shows beta wave activity is not a reliable indicator of being awake because


A) this pattern is seen in children but not adults.
B) this brain wave pattern also appears during sleep.
C) this wave form waxes and wanes during the day.
D) it can be induced by certain drugs such as alcohol.
E) drugs can elicit this brain wave pattern.

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The primary function of slow-wave sleep is to


A) clear brain waste products produced by REM sleep.
B) promote dreaming.
C) rest the brain.
D) promote brain development.
E) facilitate learning.

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The notion that REM sleep functions to promote brain development is supported by the finding that


A) newborn infants spend 70% of their sleep time in slow-wave sleep.
B) active phases of brain development are associated with low levels of REM sleep.
C) REM sleep increases in college students during exam time.
D) the elderly spend 85% of their sleep time in REM.
E) infants with well-developed brains spend proportionally less time in REM sleep than infants with poorly developed brains.

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Compare and contrast the neural systems and relevant transmitters that control slow-wave sleep.

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Slow-wave sleep is produced by activity of neurons within the ventrolateral preoptic area (vlPOA) that act by inhibition of neural systems that promote wakefulness. The vlPOA secretes GABA, which in turn inhibits transmitter systems that are key to arousal and wakefulness. These include norepinephrine within the locus coeruleus, histamine in the tuberomammillary nucleus, and serotonin within the raphe nuclei. Adenosine may promote sleep by GABA-mediated inactivation of acetylcholine neurons that promote arousal. Orexin (hypocretin) neurons promote wakefulness.

Chronic sleep deprivation can lead to


A) blocked airways.
B) obesity and diabetes.
C) psychosis.
D) mood disorder.
E) bipolar disorder.

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3- Compare the characteristics of non-REM sleep with that of REM sleep.

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Non-REM consists of four stages: stage 1...

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The sleep pattern of the dolphin is unique in that


A) slow-wave sleep is absent from its sleep pattern.
B) sleep and waking occur independently in the two hemispheres.
C) no eye movements occur in the dolphin during sleep.
D) blindness has eliminated the need of the dolphin for sleep.
E) this animal does not exhibit slow-wave sleep.

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