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The formation of bone from a cartilaginous model is termed


A) mesenchymal ossification.
B) intramembranous ossification.
C) bone remodeling.
D) orthodontia.
E) endochondral ossification.

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Which bone marking does not serve as an articulating surface?


A) Head
B) Epicondyle
C) Condyle
D) Facet
E) Trochlea

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Osteolysis is


A) demineralization due to hydrochloric acid activity.
B) the release of calcium and phosphate from the matrix.
C) the result of osteoclast activity.
D) the result of enzyme activity.
E) All of these answers are correct.

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Which is not involved in the process of bone repair following a fracture?


A) Fibroblasts produce collagen fibers to connect broken pieces of bone.
B) A fibrocartilaginous callus serves as a model for new bone growth.
C) Osteoclasts remove excess bone from the hard callus.
D) The fracture hematoma reorganizes to form a procallus.
E) No exceptions; all of the choices are involved in the process of bone repair.

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Endochondral ossification is a form of bone growth in which a cartilaginous model is replaced by bone.

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Which affects osteoblast and osteoclast activity?


A) Gravity
B) Mechanical stress
C) Calcitonin and parathyroid hormone levels
D) Blood calcium level
E) All of the choices are correct.

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About 80% of the human skeleton is replaced yearly as a result of bone remodeling.

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Which is not true about bone remodeling?


A) It occurs throughout life.
B) It assists in the maintenance of calcium and phosphate levels in the body.
C) It occurs at both the endosteal and periosteal surfaces of the bone.
D) It occurs only at articular surfaces.
E) It can occur in response to stress on a bone.

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Which region of a growing bone contains the epiphyseal plate?


A) Distal epiphysis
B) Proximal epiphysis
C) Metaphysis
D) Diaphysis
E) Periphysis

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Osteoblasts are bone-forming cells; osteoclasts are bone-dissolving cells.

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The flat bones of the cranium form by intramembranous ossification.

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During the process of endochondral ossification,chondrocytes in the cartilage model die.Why does this occur?


A) Blood supply to the cartilage is cut off by the developing periosteum.
B) Canaliculi connecting adjacent chondrocyte lacunae fuse.
C) Nutrients cannot diffuse to the chondrocytes through the calcified matrix.
D) The developing bone collar secretes enzymes that destroy the chondrocytes.
E) Phagocytic osteoclasts in the new bone engulf and destroy the chondrocytes.

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Patients with osteoporosis often suffer _________ fractures of the vertebral bodies due to loss of bone mass.


A) spiral
B) epiphyseal
C) greenstick
D) compression
E) transverse

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When during human development does the process of ossification begin?


A) 12 weeks after birth
B) 12th-13th week of embryonic development
C) 8th-9th month of fetal development
D) 3-4 months of age
E) 10-25 years of age

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The steps in the process of endochondral ossification are A: Ossification center forms in the diaphysis B: Cartilage calcifies and a bone collar forms C: Ossification centers form in the epiphyses D: Bone replaces cartilage E: Epiphyseal plates ossify F: Cartilage model develops The correct chronological order for these steps is


A) f - b - c - d - a - e
B) b - c - f - a - e - d
C) a - c - b - d - e - f
D) f - b - a - c - d - e
E) a - e - c - d - b - f

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Which is a change in bone architecture or mass related to aging?


A) Insufficient calcification
B) Demineralization
C) Reduction in the organic content of the matrix
D) Loss of flexibility and increase in brittleness
E) All of the choices are correct.

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A narrow,slit-like opening through a bone is called a _________.

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The shaft of a long bone is called the diaphysis; the ends are called the _________.

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During appositional growth of cartilage,the cells that produce the matrix are the


A) chondrocytes.
B) osteocytes.
C) fibroblasts.
D) chondroblasts.
E) osteoblasts.

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In adults,an area of compact bone called the epiphyseal tract replaces the epiphyseal plate.

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