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Logically,the following "unnatural" amino acid would be substituted for which natural amino acid in the synthesis of peptide analogs? Logically,the following  unnatural  amino acid would be substituted for which natural amino acid in the synthesis of peptide analogs?   A) Methionine B) Cysteine C) Cystine D) Tyrosine E) It could be substituted for all of these amino acids.


A) Methionine
B) Cysteine
C) Cystine
D) Tyrosine
E) It could be substituted for all of these amino acids.

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Which of these natural amino acids contains two carboxylic acid groups?


A) Aspartic acid
B) Cysteine
C) Glutamic acid
D) Cystine and cysteine
E) Aspartic acidand glutamic acid

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Which one of these amino acids does not give the usual purple color with ninhydrin?


A) Histidine
B) Proline
C) Tryptophan
D) Leucine
E) Aspartic acid

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All reactions that occur in living cells are mediated by biological catalysts called ___.The prevailing hypothesis for enzyme catalysis is called the ___ hypothesis.

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enzymes; l...

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Which of these natural amino acids,when present in a polypeptide,is likely to exhibit significant hydrogen bonding through its side chain?


A) Serine
B) Threonine
C) Tyrosine
D) Two of these choices.
E) All of these choices.

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Draw structures to represent what happens when lysine is dissolved in a strongly basic solution (pH=14).

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Which of the following would provide a synthesis of phenylalanine?


A) Phenylacetaldehyde,NH3,HCN; then H3O+ and heat
B) Potassium phthalimide,BrCH(CO2C2H5) 2; C6H5CH2Br,NaOEt; then NaOH; then HCl,heat
C) Potassium phthalimide,(C6H5) CH2CH2Br; then KOH/H2O; then HCl,heat
D) C6H5CH2COOH,SOCl2; then NH3
E) Two of these choices.

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Draw the Fischer projection of a threonine diastereomer,and label the chiral centers as R or S.

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Which amino acid would have its isoelectric point near pH 10?


A) Glycine
B) Tryptophan
C) Serine
D) Proline
E) Lysine

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Which of these amino acids is(are) R amino acid(s) ? Which of these amino acids is(are) R amino acid(s) ?   A) II and IV B) IV and V C) I and III D) V E) All of these are R amino acids.


A) II and IV
B) IV and V
C) I and III
D) V
E) All of these are R amino acids.

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Which amino acid is unlikely to be found in a natural protein? Which amino acid is unlikely to be found in a natural protein?   A) IV B) III C) II D) V E) I


A) IV
B) III
C) II
D) V
E) I

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What is the pI of the following amino acid? What is the pI of the following amino acid?   A) 1.5 B) 6.3 C) 5.6 D) 9.8 E) 7.2


A) 1.5
B) 6.3
C) 5.6
D) 9.8
E) 7.2

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What is the pI of the following amino acid? What is the pI of the following amino acid?   A) 1.2 B) 3.2 C) 5.5 D) 6.2 E) 7.0


A) 1.2
B) 3.2
C) 5.5
D) 6.2
E) 7.0

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Show how a Strecker synthesis might be used to prepare phenylalanine starting from phenylacetaldehyde.

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Which of these amino acids is described as an "essential" amino acid?


A) Methionine
B) Phenylalanine
C) Isoleucine
D) Tryptophan
E) All of these are "essential" amino acids.

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Draw structures to represent what happens when valine is dissolved in a strongly acidic solution (pH=0).

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Enzymes catalyze stereospecific reactions.Stereospecific reactions are those that:


A) Lead to different stereoisomers from different stereoisomeric substrates.
B) Lead to the same stereoisomer despite starting with different stereoisomeric substrates.
C) Both stereoisomers,cis or trans can produce identical products.
D) Transform different substrates.
E) Transform one conformer into another conformer by rotation of the bonds.

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Which amino acid is achiral? Which amino acid is achiral?   A) I B) II C) III D) IV E) V


A) I
B) II
C) III
D) IV
E) V

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What is the pI of phenylalanine (pKa1 = 1.8; pKa2= 9.1) ?


A) 2.3
B) 1.8
C) 5.5
D) 9.1
E) 10.9

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Which amino acid would have its isoelectric point near pH 10? Which amino acid would have its isoelectric point near pH 10?   A) I B) II C) III D) IV E) V


A) I
B) II
C) III
D) IV
E) V

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